Shmt2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
MGI:1277989

15 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Shmt2^em1(IMPC)Bay/Shmt2⁺ C57BL/6N-Shmt2^em1(IMPC)Bay/Bay	abnormal optic disk morphology	J:211773
	abnormal retina blood vessel morphology	J:211773
	increased cornea thickness	J:211773
	increased spleen weight	J:211773
	prolonged PR interval	J:211773
Shmt2^em1(IMPC)Bay/Shmt2^em1(IMPC)Bay C57BL/6N-Shmt2^em1(IMPC)Bay/Bay	abnormal embryo size	J:211773
	abnormal placenta size	J:211773
	pallor	J:211773
	prenatal lethality	J:211773
	preweaning lethality, complete penetrance	J:211773
Shmt2^em1Jiha/Shmt2^em1Jiha involves: C57BL/6JJcl	abnormal respiratory electron transport chain	J:259713
	anemia	J:259713
	decreased embryo size	J:259713
	decreased fibroblast proliferation	J:259713
	lethality throughout fetal growth and development, complete penetrance	J:259713

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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