Slc6a2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc6a2
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
MGI:1270850

30 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc6a2^tm1.1Hhg/Slc6a2^tm1.1Hhg B6.129P2(Cg)-Slc6a2^tm1.1Hhg	impaired behavioral response to cocaine	J:101977
	impaired behavioral response to xenobiotic	J:101977
Slc6a2^tm1.1Mkh/Slc6a2⁺ B6.129S6-Slc6a2^tm1.1Mkh	abnormal noradrenaline level	J:200046
	behavioral despair	J:200046
	normal cardiovascular system phenotype	J:200046
	increased anxiety-related response	J:200046
	increased circulating noradrenaline level	J:200046
	increased heart rate	J:200046
	increased thigmotaxis	J:200046
	normal nervous system phenotype	J:200046
Slc6a2^tm1.1Mkh/Slc6a2^tm1.1Mkh B6.129S6-Slc6a2^tm1.1Mkh	abnormal noradrenaline level	J:200046
	increased circulating adrenaline level	J:200046
	increased dopamine level	J:200046
Slc6a2^{tm1b(EUCOMM)Hmgu}/Slc6a2⁺ C57BL/6N-Slc6a2^{tm1b(EUCOMM)Hmgu}/H	decreased hemoglobin content	J:211773
	impaired glucose tolerance	J:211773
Slc6a2^{tm1b(EUCOMM)Hmgu}/Slc6a2^{tm1b(EUCOMM)Hmgu} C57BL/6N-Slc6a2^{tm1b(EUCOMM)Hmgu}/H	abnormal gait	J:211773
	preweaning lethality, incomplete penetrance	J:211773
	small heart	J:211773
Slc6a2^tm1Mca/Slc6a2^tm1Mca B6.129S4-Slc6a2^tm1Mca	enhanced long-term potentiation	J:89778
Slc6a2^tm1Mca/Slc6a2^tm1Mca involves: 129S4/SvJaeSor	abnormal noradrenaline level	J:66729
	abnormal physiological response to xenobiotic	J:66729
	decreased locomotor activity	J:66729
	decreased vertical activity	J:66729
	increased chemically-elicited antinociception	J:66729
	increased thermal nociceptive threshold	J:66729
Slc6a2^tm1Mca/Slc6a2^tm1Mca involves: 129S4/SvJaeSor * C57BL/6J	abnormal emotion/affect behavior	J:61825
	abnormal nervous system physiology	J:61825
	decreased body temperature	J:61825
	decreased body weight	J:61825
	enhanced behavioral response to addictive substance	J:61825
	enhanced behavioral response to cocaine	J:61825
	increased physiological sensitivity to xenobiotic	J:61825

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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