Apba2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Apba2
amyloid beta precursor protein binding family A member 2
MGI:1261791

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apba1^tm1.1Sud/Apba1^tm1.1Sud Apba2^tm1.1Sud/Apba2^tm1.1Sud involves: 129S1/Sv * 129X1/SvJ	abnormal CNS synaptic transmission	J:115573
	abnormal excitatory postsynaptic currents	J:115573
	ataxia	J:115573
	decreased body size	J:115573
	decreased body weight	J:115573
	enhanced paired-pulse facilitation	J:115573
	neonatal lethality, incomplete penetrance	J:115573
Apba1^tm1.1Sud/Apba1^tm1.1Sud Apba2^tm1.1Sud/Apba2^tm1.1Sud Apba3^tm1.1Sud/Apba3^tm1.1Sud involves: 129S1/Sv * 129X1/SvJ	abnormal CNS synaptic transmission	J:115573
	abnormal inhibitory postsynaptic currents	J:115573
	neonatal lethality, incomplete penetrance	J:115573
Apba2^tm1Tsuz/Apba2^tm1Tsuz Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-APBA2,-lacZ)1Ito/0 B6.Cg-Apba2^tm1Tsuz Tg(Camk2a-tTA)1Mmay Tg(tetO-APBA2,-lacZ)1Ito	abnormal response to novel object	J:148481
	abnormal social investigation	J:148481
	decreased locomotor activity	J:148481
	increased anxiety-related response	J:148481

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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