Sorl1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sorl1
sortilin-related receptor, LDLR class A repeats-containing
MGI:1202296

13 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sorl1^Gt(Ex255)Byg/Sorl1^Gt(Ex255)Byg B6.129P2-Sorl1^Gt(Ex255)Byg	amyloid beta deposits	J:125747
Sorl1^{tm1b(EUCOMM)Wtsi}/Sorl1^{tm1b(EUCOMM)Wtsi} C57BL/6N-Sorl1^{tm1b(EUCOMM)Wtsi}/H	abnormal gait	J:211773
	abnormal retina morphology	J:211773
	abnormal snout morphology	J:211773
	enlarged seminal vesicle	J:211773
Sorl1^tm1Bujo/Sorl1^tm1Bujo involves: 129/Sv * C57BL/6	abnormal vascular smooth muscle physiology	J:140878
Sorl1^tm1Bujo/Sorl1^tm1Bujo involves: 129/Sv * C57BL/6	abnormal vascular wound healing	J:140878
Sorl1^tm1Tew/Sorl1^tm1Tew either: (involves: 129/SvEmcTer * BALB/c) or (involves: 129/SvEmcTer * C57BL/6N)	amyloid beta deposits	J:101417
	normal nervous system phenotype	J:101417
Sorl1^tm1Tew/Sorl1^tm1Tew involves: 129 * C57BL/6 * SJL	abnormal cholinergic neuron morphology	J:210074
	abnormal object recognition memory	J:210074
	amyloid beta deposits	J:210074
	impaired spatial learning	J:210074
	neuron degeneration	J:210074
	tau protein deposits	J:210074

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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