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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Scarb2
scavenger receptor class B, member 2
MGI:1196458
59 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Scarb2em2(IMPC)Tcp/Scarb2em2(IMPC)Tcp
C57BL/6NCrl-Scarb2em2(IMPC)Tcp/Tcp
decreased body length J:211773
decreased bone mineral density J:211773
decreased grip strength J:211773
decreased lean body mass J:211773
decreased mean corpuscular volume J:211773
decreased total body fat amount J:211773
enlarged kidney J:211773
enlarged lymph nodes J:211773
increased bone mineral content J:211773
increased circulating potassium level J:211773
increased lean body mass J:211773
increased leukocyte cell number J:211773
thrombocytosis J:211773
Scarb2tm1Psa/Scarb2tm1Psa
involves: 129P2/OlaHsd * C57BL/6J
abnormal auditory brainstem response J:82474, J:121998
abnormal distortion product otoacoustic emission J:121998
abnormal nervous system morphology J:82474
abnormal otolithic membrane morphology J:82474
abnormal phrenic nerve morphology J:82474
abnormal Schwann cell morphology J:82474
abnormal stria vascularis morphology J:82474, J:121998
abnormal stria vascularis vasculature morphology J:121998
abnormal strial marginal cell morphology J:82474, J:121998
abnormal ureter morphology J:82474
abnormal ureter smooth muscle morphology J:82474
abnormal ureteropelvic junction morphology J:82474
abnormal urothelium morphology J:82474
abnormal vestibular hair cell physiology J:121998
absent endocochlear potential J:82474
absent otoliths J:82474
absent startle reflex J:82474
albuminuria J:82474
cochlear ganglion degeneration J:82474, J:121998
cochlear inner hair cell degeneration J:82474
cochlear outer hair cell degeneration J:82474
deafness J:82474
decreased endocochlear potential J:82474
decreased urine glucose level J:82474
decreased urine osmolality J:82474
demyelination J:82474
dilated kidney calyx J:82474
distended abdomen J:82474
hydronephrosis J:82474
leukocyturia J:82474
polydipsia J:82474
polyuria J:82474
premature death J:82474
sensorineural hearing loss J:121998
stria vascularis degeneration J:82474, J:121998
ureteropelvic junction obstruction J:82474
Scarb2tm1Psa/Scarb2tm1Psa
involves: 129P2/OlaHsd * C57BL/6N
abnormal behavior J:216676
abnormal enzyme/coenzyme activity J:216676
abnormal nervous system morphology J:216676
abnormal neuron morphology J:216676
astrocytosis J:216676
decreased body weight J:216676
limb grasping J:216676
microgliosis J:216676
neurodegeneration J:216676
paralysis J:216676
premature death J:216676
tremors J:216676

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory