72 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Polgtm1.1Lrsn/Polgtm1.1Lrsn involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal mitochondrial ATP synthesis coupled electron transport	J:91077
	abnormal myocardial fiber morphology	J:91077
	alopecia	J:91077
	azoospermia	J:91077
	decreased hemoglobin content	J:91077
	decreased subcutaneous adipose tissue amount	J:91077
	decreased total body fat amount	J:91077
	dilated heart left ventricle	J:91077
	hypochromic macrocytic anemia	J:91077
	increased heart weight	J:91077
	increased mitochondrial size	J:91077
	kyphosis	J:91077
	oligozoospermia	J:91077
	osteoporosis	J:91077
	premature death	J:91077
	reduced female fertility	J:91077
	reduced male fertility	J:91077
	seminiferous tubule degeneration	J:91077
	small testis	J:91077
	weight loss	J:91077
Polgtm1.2Lrsn/Polgtm1.2Lrsn involves: 129S1/Sv * 129X1/SvJ	decreased embryo size	J:99794
	embryonic growth retardation	J:99794
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:99794
Polgtm1Jiha/Polg+ involves: C57BL/6JJcl	abnormal bone marrow cell physiology	J:199416
	abnormal oxidative phosphorylation	J:199416
	increased B cell derived lymphoma incidence	J:199416
	increased incidence of induced tumors	J:199416
	normal mortality/aging	J:199416
	oxidative stress	J:199416
Polgtm1Jiha/Polgtm1Jiha involves: C57BL/6JJcl	abnormal oxidative phosphorylation	J:199416
	decreased circulating glucose level	J:199416
	increased circulating lactate level	J:199416
	normal integument phenotype	J:199416
	kyphosis	J:199416
	premature death	J:199416
Polgtm1Prol/Polgtm1Prol B6J.129S7-Polgtm1Prol	abnormal erythroid lineage cell morphology	J:154187
	abnormal lymphopoiesis	J:154187
	abnormal mitochondrial physiology	J:154187
	decreased double-positive T cell number	J:154187
	decreased hemoglobin content	J:154187
	decreased immature B cell number	J:154187
	decreased lymphocyte cell number	J:154187
	decreased mature B cell number	J:154187
	decreased pre-B cell number	J:154187
	decreased pro-B cell number	J:154187
	decreased thymocyte number	J:154187
	increased erythroblast number	J:154187
	increased mean corpuscular volume	J:154187
	macrocytic anemia	J:154187
	macrocytosis	J:154187
	premature death	J:154187
Polgtm1Prol/Polgtm1Prol involves: 129S7/SvEvBrd * C57BL/6J * ICR	abnormal coat/hair pigmentation	J:99764
	abnormal crypts of Lieberkuhn morphology	J:99764
	abnormal mitochondrial physiology	J:119971
	abnormal thymus involution	J:99764
	cochlear ganglion degeneration	J:99764, J:119971
	cochlear hair cell degeneration	J:119971
	cochlear outer hair cell degeneration	J:119971
	decreased erythrocyte cell number	J:99764
	decreased skeletal muscle mass	J:99764
	increased apoptosis	J:99764
	increased or absent threshold for auditory brainstem response	J:99764
	increased susceptibility to age-related hearing loss	J:99764, J:119971
	kyphosis	J:99764
	osteoporosis	J:99764
	premature aging	J:99764
	premature death	J:99764
	premature hair loss	J:99764
	stria vascularis degeneration	J:119971
	testicular atrophy	J:99764
	weight loss	J:99764
Tg(Camk2a-Polg*D181A)BTkato/0 C57BL/6J-Tg(Camk2a-Polg*D181A)BTkato	abnormal dopamine level	J:127895
	abnormal mitochondrial chromosome morphology	J:127895
	abnormal ultradian rhythm behavior	J:127895
	abnormal voluntary movement	J:127895
	normal behavior/neurological phenotype	J:127895
	decreased body weight	J:127895
	decreased food intake	J:127895
	decreased noradrenaline level	J:127895
	decreased serotonin level	J:127895
	increased fear-related response	J:127895
	increased startle reflex	J:127895