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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Sptlc1
serine palmitoyltransferase, long chain base subunit 1
MGI:1099431
26 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Tg(CAG-Spltc1)6FAmcc/0
involves: C3H * C57BL/6
abnormal male germ cell morphology J:155748
normal behavior/neurological phenotype J:155748
impaired coordination J:155748
normal nervous system phenotype J:155748
Tg(CAG-SPTLC1*C133W)8EAmcc/0
involves: C3H * C57BL/6
abnormal axon morphology J:106812
abnormal behavior J:106812
abnormal defecation J:106812
abnormal intestinal transit time J:106812
abnormal myelin sheath morphology J:106812, J:155748
abnormal neurite morphology J:106812
abnormal pancreas morphology J:106812
abnormal Schwann cell morphology J:155748
abnormal sperm motility J:155748
abnormal spermatogenesis J:106812
abnormal ventral spinal root morphology J:106812
decreased body size J:106812
decreased testis weight J:155748
decreased thermal nociceptive threshold J:106812
exocrine pancreas atrophy J:106812
hyperalgesia J:155748
impaired coordination J:155748
normal limbs/digits/tail phenotype J:106812
microgliosis J:155748
neuron degeneration J:155748
oligozoospermia J:155748
reduced fertility J:106812, J:155748
normal reproductive system phenotype J:106812

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory