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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		E2f2
E2F transcription factor 2
MGI:1096341
18 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
E2f1tm1Meg/E2f1tm1Meg
E2f2tm1Zubi/E2f2tm1Zubi
E2f3tm2.1Gle/E2f3tm2.1Gle
involves: 129 * FVB/N * NIH Black Swiss 		decreased cell proliferation J:138289
perinatal lethality J:138289
E2f1tm1Meg/E2f1tm1Meg
E2f2tm1Zubi/E2f2tm1Zubi
E2f3tm3.1Gle/E2f3tm3.1Gle
involves: 129 * FVB/N * NIH Black Swiss 		decreased body weight J:138289
decreased cell proliferation J:138289
normal mortality/aging J:138289
E2f2tm1Zubi/E2f2tm1Zubi
E2f3tm2.1Gle/E2f3tm2.1Gle
involves: 129S1/Sv * 129S6/SvEvTac * FVB/N * NIH Black Swiss 		no abnormal phenotype detected J:138289
E2f2tm1Zubi/E2f2tm1Zubi
E2f3tm3.1Gle/E2f3tm3.1Gle
involves: 129S1/Sv * 129S6/SvEvTac * FVB/N * NIH Black Swiss 		no abnormal phenotype detected J:138289
E2f2tm1Zubi/E2f2tm1Zubi
Rbl1tm1Htr/Rbl1tm1Htr
Tg(Pax6-cre,GFP)2Pgr/?
involves: 129 * C57BL/6 * FVB/N * NMRI 		abnormal eye development J:124204
abnormal retina bipolar cell morphology J:124204
decreased retina ganglion cell number J:124204
decreased retina rod cell number J:124204
E2f2tm1Zubi/E2f2tm1Zubi
Tg(TcraH-Y,TcrbH-Y)71Vbo/?
involves: 129S1/Sv * C57BL/6 * C57BL/6J * DBA/2J 		abnormal immune system morphology J:76318
abnormal immune system physiology J:76318
enlarged spleen J:76318
increased CD8-positive, alpha-beta T cell number J:76318
increased inflammatory response J:76318
increased susceptibility to autoimmune disorder J:76318
increased T cell proliferation J:76318
premature death J:76318
thymus hypoplasia J:76318
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory