Nudt1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nudt1
nudix hydrolase 1
MGI:109280

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Msh2^tm1Tts/Msh2^tm1Tts Nudt1^tm1Tts/Nudt1^tm1Tts involves: 129S/SvEv * C57BL/6J	abnormal cell physiology	J:79732
Mutyh^tm1Yun/Mutyh^tm1Yun Nudt1^tm1Tts/Nudt1^tm1Tts Ogg1^tm1Yun/Ogg1^tm1Yun B6JJcl.129-Mutyh^tm1Yun Nudt1^tm1Tts Ogg1^tm1Yun	increased tumor incidence	J:193978
Nudt1^tm1Tts/Nudt1^tm1Tts Ogg1^tm1Yun/Ogg1^tm1Yun involves: 129S/SvEv * C57BL/6J	normal neoplasm	J:82287
Nudt1^tm1Tts/Nudt1^tm1Tts Ogg1^tm1Yun/Ogg1^tm1Yun involves: 129S/SvEv * C57BL/6JJcl	abnormal motor capabilities/coordination/movement	J:193978
	abnormal single-strand DNA break repair	J:193978
	decreased locomotor activity	J:193978
	decreased vertical activity	J:193978
	increased susceptibility to neuronal excitotoxicity	J:193978
	microgliosis	J:193978
	neurodegeneration	J:193978

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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