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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
MGI:107799
40 phenotypes from 1 allele in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Gadd45atm1Ajf/Gadd45atm1Ajf
either: (involves: 129P2/OlaHsd * C57BL/6 * SKH1) or (involves: 129X1/SvJ * C57BL/6 * SKH1)
increased incidence of tumors by UV-induction J:81080
increased sensitivity to skin irradiation J:81080
Gadd45atm1Ajf/Gadd45atm1Ajf
either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129X1/SvJ * C57BL/6)
abnormal bone marrow cell morphology/development J:102680
abnormal cell nucleus morphology J:57882
abnormal cell physiology J:57882
abnormal centrosome morphology J:57882
abnormal chromosome morphology J:57882
abnormal chromosome number J:57882
abnormal lymphopoiesis J:76041
abnormal mitosis J:57882
aneuploidy J:57882
decreased basophil cell number J:76041
decreased eosinophil cell number J:76041
decreased leukocyte cell number J:76041
decreased lymphocyte cell number J:76041
decreased mitotic index J:57882
decreased sensitivity to skin irradiation J:81080
dilated proximal convoluted tubule J:76041
exencephaly J:57882
glomerulonephritis J:76041
increased anti-double stranded DNA antibody level J:76041
increased anti-histone antibody level J:76041
increased anti-single stranded DNA antibody level J:76041
increased autoantibody level J:76041
increased fibroblast proliferation J:57882
increased IgG1 level J:76041
increased IgM level J:76041
increased incidence of tumors by ionizing radiation induction J:57882
increased inflammatory response J:76041
increased kidney cell proliferation J:76041
increased mesangial cell number J:76041
increased T cell number J:76041
increased T cell proliferation J:76041
increased thymocyte number J:57882
increased thymus weight J:57882
increased urine protein level J:76041
mesangial cell interposition J:76041
parturition failure J:57882
premature death J:76041
Gadd45atm1Ajf/Gadd45atm1Ajf
involves: 129
abnormal base-excision repair J:101710

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory