Tank Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tank
TRAF family member-associated Nf-kappa B activator
MGI:107676

23 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Tank^tm1Aki/Tank^tm1Aki involves: 129/Sv * C57BL/6	abnormal dendritic cell physiology	J:151757
	abnormal macrophage physiology	J:151757
	abnormal plasmacytoid dendritic cell physiology	J:151757
	glomerulonephritis	J:151757
	increased anti-double stranded DNA antibody level	J:151757
	increased anti-nuclear antigen antibody level	J:151757
	increased B cell proliferation	J:151757
	increased IgA level	J:151757
	increased IgG1 level	J:151757
	increased IgG2a level	J:151757
	increased IgG2b level	J:151757
	increased IgM level	J:151757
	increased interferon-alpha secretion	J:151757
	increased interleukin-6 secretion	J:151757
	increased mature B cell number	J:151757
	increased plasma cell number	J:151757
	increased tumor necrosis factor secretion	J:151757
	liver inflammation	J:151757
	lung inflammation	J:151757
	lymph node hyperplasia	J:151757
	premature death	J:151757
	renal glomerular immunoglobulin deposits	J:151757
	spleen hyperplasia	J:151757

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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