Plcb2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plcb2
phospholipase C, beta 2
MGI:107465

16 phenotypes from 2 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Plcb2^{tm1b(KOMP)Wtsi}/Plcb2^{tm1b(KOMP)Wtsi} C57BL/6N-Plcb2^{tm1b(KOMP)Wtsi}/MbpMmucd	decreased pulmonary ventilation	J:211773
Plcb2^{tm1b(KOMP)Wtsi}/Plcb2^{tm1b(KOMP)Wtsi} C57BL/6N-Plcb2^{tm1b(KOMP)Wtsi}/Ucd	abnormal spleen morphology	J:211773
	abnormal vocalization	J:211773
	decreased locomotor activity	J:211773
	enlarged spleen	J:211773
	male infertility	J:211773
Plcb2^tm1Dwu/Plcb2^tm1Dwu B6.129S1-Plcb2^tm1Dwu/J	abnormal sensory capabilities/reflexes/nociception	J:223366
Plcb2^tm1Dwu/Plcb2^tm1Dwu B6.129S1-Plcb2^tm1Dwu/J	abnormal vomeronasal sensory neuron physiology	J:223366
Plcb2^tm1Dwu/Plcb2^tm1Dwu involves: 129	abnormal leukocyte physiology	J:41948
	decreased susceptibility to bacterial infection	J:41948
	decreased susceptibility to infection	J:41948
	decreased susceptibility to viral infection	J:41948
Plcb2^tm1Dwu/Plcb2^tm1Dwu involves: 129/Sv * SWR	abnormal bitter taste sensitivity	J:82314
	abnormal gustatory system physiology	J:82314
	abnormal sweet taste sensitivity	J:82314
	abnormal taste sensitivity	J:82314

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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