Pon2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pon2
paraoxonase 2
MGI:106687

13 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pon2^Gt(XE661)Byg/Pon2^Gt(XE661)Byg B6.129P2-Pon2^Gt(XE661)Byg	abnormal cholesterol homeostasis	J:116935
	abnormal circulating protein level	J:116935
	abnormal enzyme/coenzyme activity	J:116935
	abnormal macrophage chemotaxis	J:116935
	abnormal macrophage physiology	J:116935
	decreased circulating cholesterol level	J:116935
	decreased circulating LDL cholesterol level	J:116935
	decreased circulating VLDL cholesterol level	J:116935
	increased susceptibility to atherosclerosis	J:116935
	increased susceptibility to bacterial infection	J:116935
	oxidative stress	J:116935
Pon2^{tm1b(EUCOMM)Hmgu}/Pon2^{tm1b(EUCOMM)Hmgu} C57BL/6N-Pon2^{tm1b(EUCOMM)Hmgu}/H	decreased circulating serum albumin level	J:211773
	decreased neutrophil cell number	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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