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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Six5
sine oculis-related homeobox 5
MGI:106220
16 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Six5tm1Rdd/Six5+
129S4/SvJae-Six5tm1Rdd
abnormal testis morphology J:91207
increased circulating follicle stimulating hormone level J:91207
nuclear cataract J:61881
oligozoospermia J:91207
seminiferous tubule degeneration J:91207
small seminiferous tubules J:91207
Six5tm1Rdd/Six5+
involves: 129S4/SvJae * C57BL/6
cataract J:61881
Six5tm1Rdd/Six5tm1Rdd
129S4/SvJae-Six5tm1Rdd
abnormal spermatid morphology J:91207
abnormal spermatogenesis J:91207
abnormal spermiogenesis J:91207
abnormal testis morphology J:91207
azoospermia J:91207
decreased Sertoli cell number J:91207
increased circulating follicle stimulating hormone level J:91207
increased Leydig cell number J:91207
male infertility J:91207
nuclear cataract J:61881
seminiferous tubule degeneration J:91207
small seminiferous tubules J:91207
small testis J:91207
Six5tm1Rdd/Six5tm1Rdd
involves: 129S4/SvJae * C57BL/6
cataract J:61881
Six5tm1Tap/Six5+
involves: 129/Sv * C57BL/6
cataract J:61882
Six5tm1Tap/Six5tm1Tap
involves: 129/Sv * C57BL/6
cataract J:61882
normal muscle phenotype J:61882

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory