Hsd17b1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hsd17b1
hydroxysteroid (17-beta) dehydrogenase 1
MGI:105077

29 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hsd17b1^{tm1(KOMP)Vlcg}/Hsd17b1^{tm1(KOMP)Vlcg} involves: C57BL/6NTac	abnormal corpus luteum morphology	J:225533
	abnormal ovary morphology	J:225533
	abnormal progesterone level	J:225533
	abnormal uterus weight	J:225533
	decreased corpora lutea number	J:225533
	decreased litter size	J:225533
	delayed vaginal opening	J:225533
	increased luteinizing hormone level	J:225533
	increased ovary weight	J:225533
	reduced female fertility	J:225533
	normal reproductive system phenotype	J:225533
Hsd17b1^{tm1.1(KOMP)Vlcg}/Hsd17b1^{tm1.1(KOMP)Vlcg} C57BL/6N-Hsd17b1^{tm1.1(KOMP)Vlcg}/J	abnormal lens morphology	J:211773
	abnormal motor coordination/balance	J:211773
	abnormal retina morphology	J:211773
	abnormal sleep behavior	J:211773
	decreased circulating chloride level	J:211773
	decreased circulating glucose level	J:211773
	decreased circulating serum albumin level	J:211773
	decreased erythrocyte cell number	J:211773
	decreased hematocrit	J:211773
	decreased hemoglobin content	J:211773
	decreased mean corpuscular volume	J:211773
	decreased total body fat amount	J:211773
	decreased vertical activity	J:211773
	impaired righting response	J:211773
	increased bone mineral content	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating potassium level	J:211773
	increased heart weight	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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