Adra1b Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Adra1b
adrenergic receptor, alpha 1b
MGI:104774

17 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Adra1a^tm1Pcs/Adra1a^tm1Pcs Adra1b^tm1Cta/Adra1b^tm1Cta B6.129-Adra1b^tm1Cta Adra1a^tm1Pcs	decreased myocardial fiber size	J:83876
	small heart	J:83876
Adra1a^tm1Pcs/Adra1a^tm1Pcs Adra1b^tm1Cta/Adra1b^tm1Cta involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N	abnormal cardiac muscle contractility	J:102648
	abnormal cardiovascular system physiology	J:83876
	abnormal heart size	J:83876
	abnormal myocardial fiber physiology	J:102648
	congestive heart failure	J:83876
	decreased cardiac output	J:83876
	decreased cardiac stroke volume	J:83876
	decreased heart rate	J:83876
	decreased heart weight	J:83876
	decreased myocardial fiber size	J:83876
	enlarged kidney	J:83876
	impaired exercise endurance	J:83876
	increased cardiac muscle contractility	J:83876
	increased left ventricle developed pressure	J:102648
	increased response of heart to induced stress	J:83876
	increased susceptibility to induced morbidity/mortality	J:83876
	small heart	J:83876

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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