Sez6 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sez6
seizure related gene 6
MGI:104745

13 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sez6^tm1.1Sest/Sez6^tm1.1Sest involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal CNS synaptic transmission	J:132725
	abnormal dendrite morphology	J:132725
	abnormal excitatory postsynaptic currents	J:132725
	abnormal excitatory postsynaptic potential	J:132725
	abnormal locomotor behavior	J:132725
	abnormal neurite morphology	J:132725
	abnormal spatial learning	J:132725
	decreased locomotor activity	J:132725
	decreased susceptibility to pharmacologically induced seizures	J:132725
	decreased vertical activity	J:132725
	impaired coordination	J:132725
	impaired swimming	J:132725
Sez6^tm1Hta/Sez6^tm1Hta involves: 129 * C57BL	no abnormal phenotype detected	J:111556

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23