Cplx2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cplx2
complexin 2
MGI:104726

15 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cplx1^tm2Bros/Cplx1^tm2Bros Cplx2^tm1Bros/Cplx2^tm1Bros Not Specified	abnormal CNS synaptic transmission	J:86365
	abnormal inhibitory postsynaptic currents	J:136393
	abnormal neuron physiology	J:136393
	abnormal neurotransmitter secretion	J:136393
	abnormal pre-Botzinger complex physiology	J:136393
	decreased excitatory postsynaptic current amplitude	J:136393
	decreased miniature excitatory postsynaptic current amplitude	J:136393
	decreased miniature excitatory postsynaptic current frequency	J:136393
	impaired synaptic plasticity	J:136393
	neonatal lethality, complete penetrance	J:86365, J:136393
Cplx1^tm2Bros/Cplx1^tm2Bros Cplx2^tm1Bros/Cplx2^tm1Bros Cplx3^tm1Bros/Cplx3^tm1Bros Not Specified	abnormal inhibitory postsynaptic currents	J:136393
	abnormal miniature excitatory postsynaptic currents	J:136393
	abnormal neuron physiology	J:136393
	abnormal neurotransmitter secretion	J:136393
	abnormal pre-Botzinger complex physiology	J:136393
	decreased excitatory postsynaptic current amplitude	J:136393
	decreased excitatory postsynaptic current frequency	J:136393
	impaired synaptic plasticity	J:136393
	neonatal lethality, complete penetrance	J:136393
Cplx2^tm1Bros/Cplx2^tm1Bros Cplx3^tm1Bros/Cplx3^tm1Bros Not Specified	normal mortality/aging	J:136393
	normal nervous system phenotype	J:136393
	normal reproductive system phenotype	J:136393

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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