Man2a1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Man2a1
mannosidase 2, alpha 1
MGI:104669

14 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Man2a1^tm1Jxm/Man2a1^tm1Jxm Man2a2^tm1Mfu/Man2a2^tm1Mfu involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal breathing pattern	J:111055
	abnormal liver morphology	J:111055
	abnormal proximal convoluted tubule morphology	J:111055
	abnormal pulmonary alveolus epithelial cell morphology	J:111055
	abnormal pulmonary alveolus morphology	J:111055
	lethality throughout fetal growth and development, incomplete penetrance	J:111055
	neonatal lethality, incomplete penetrance	J:111055
	postnatal lethality, incomplete penetrance	J:111055
Man2a1^tm1Jxm/Man2a1^tm1Jxm Rag1^tm1Mom/Rag1^tm1Mom B6.129-Rag1^tm1Mom Man2a1^tm1Jxm	abnormal nephron morphology	J:124348
	alopecia	J:124348
	increased mesangial cell apoptosis	J:124348
	increased urine protein level	J:124348
	kidney inflammation	J:124348
	weight loss	J:124348

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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