About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tle4
transducin-like enhancer of split 4
MGI:104633
47 phenotypes from 2 alleles in 2 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Tle4em1(IMPC)Mbp/Tle4em1(IMPC)Mbp
C57BL/6NCrl-Tle4em1(IMPC)Mbp/Mmucd
abnormal auditory brainstem response J:211773
abnormal eye morphology J:211773
abnormal kidney morphology J:211773
abnormal liver morphology J:211773
abnormal lymph node morphology J:211773
abnormal rectum morphology J:211773
abnormal skin morphology J:211773
abnormal spleen morphology J:211773
decreased grip strength J:211773
decreased heart weight J:211773
decreased prepulse inhibition J:211773
enlarged liver J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
impaired glucose tolerance J:211773
male infertility J:211773
small kidney J:211773
Tle4tm1.2Dasw/Tle4tm1.2Dasw
B6.129S6(Cg)-Tle4tm1.2Dasw
abnormal hematopoietic stem cell physiology J:219243
abnormal long bone epiphyseal plate morphology J:219243
abnormal long bone epiphyseal plate proliferative zone J:219243
abnormal long bone hypertrophic chondrocyte zone J:219243
abnormal lymphopoiesis J:219243
abnormal spleen B cell follicle morphology J:219243
abnormal thymus morphology J:219243
decreased B cell number J:219243
decreased body weight J:219243
decreased bone marrow cell number J:219243
decreased bone mineral content J:219243
decreased common myeloid progenitor cell number J:219243
decreased compact bone thickness J:219243
decreased DN2 thymocyte number J:219243
decreased double-positive T cell number J:219243
decreased follicular B cell number J:219243
decreased hematopoietic stem cell number J:219243
decreased leukocyte cell number J:219243
decreased long bone epiphyseal plate size J:219243
decreased lymphocyte cell number J:219243
decreased pre-pro B cell number J:219243
decreased trabecular bone mass J:219243
normal immune system phenotype J:219243
increased NK T cell number J:219243
increased thymocyte apoptosis J:219243
postnatal growth retardation J:219243
premature death J:219243
spleen hypoplasia J:219243
thymus atrophy J:219243
thymus hypoplasia J:219243

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/17/2022
MGI 6.19
The Jackson Laboratory