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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tnnt2
troponin T2, cardiac
MGI:104597
24 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Plntm1Egk/Plntm1Egk
Tnnt2tm2.1Feah/Tnnt2+
involves: 129S2/SvPas * 129S6/SvEvTac * FVB/N
decreased cardiac muscle contractility J:243725
dilated cardiomyopathy J:243725
dilated heart left ventricle J:243725
Tg(Myh6-TNNT2)3Jdp/0
involves: C57BL/6 * SJL
normal cardiovascular system phenotype J:67284
Tg(Myh6-TNNT2*I79N)8Jdp/0
involves: C57BL/6 * SJL
abnormal cardiovascular system physiology J:213305
abnormal heart morphology J:213305
abnormal myocardial fiber physiology J:67284
decreased heart weight J:67284
normal mortality/aging J:67284
prolonged QRS complex duration J:213305
ventricular premature beat J:213305
ventricular tachycardia J:213305
Tg(Myh6-TNNT2*I79N)9Jdp/0
involves: C57BL/6 * SJL
abnormal myocardial fiber physiology J:67284
decreased heart weight J:67284
normal mortality/aging J:67284
Tg(Myh6-TNNT2*R92Q)#Ajm/0
involves: C3H * C57BL/6 * ICR
abnormal cardiovascular system physiology J:161899
abnormal heart left ventricle morphology J:161899
abnormal myocardial fiber morphology J:161899, J:162685
cardiac interstitial fibrosis J:161899, J:162685
normal cardiovascular system phenotype J:161899
normal mortality/aging J:161899
Tg(Myh6-TNNT2*R141W)#Ajm/0
involves: C3H * C57BL/6 * ICR
abnormal cardiovascular system physiology J:161899
abnormal heart left ventricle morphology J:161899
cardiac hypertrophy J:161899
cardiac interstitial fibrosis J:161899
enlarged heart J:161899
increased heart weight J:161899
increased left ventricle weight J:161899
premature death J:161899
Tg(Myh6-TNNT2*R141W)#Lian/0
involves: C57BL/6J
abnormal heart left ventricle morphology J:211769
abnormal myocardial fiber morphology J:211769
abnormal thrombosis J:211769
cardiac hypertrophy J:211769
cardiac interstitial fibrosis J:211769
decreased cardiac muscle contractility J:211769
dilated cardiomyopathy J:211769
dilated heart ventricle J:211769
premature death J:211769
thin ventricular wall J:211769
Tg(Tnnt2-TNNT2*R92Q)#Ajm/0
involves: C3H * C57BL/6 * ICR
abnormal blood flow velocity J:117554
abnormal cardiovascular system physiology J:117554
abnormal myocardial fiber morphology J:117554
cardiac interstitial fibrosis J:117554
Tg(Tnnt2-TNNT2*R92Q)M-2Ajm/0
involves: C3H * C57BL/6 * ICR
abnormal blood flow velocity J:117554
abnormal cardiovascular system physiology J:117554
abnormal myocardial fiber morphology J:117554
cardiac interstitial fibrosis J:117554

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/04/2019
MGI 6.14
The Jackson Laboratory