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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Atp6v1b1
ATPase, H+ transporting, lysosomal V1 subunit B1
MGI:103285
33 phenotypes from 3 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Atp6v1b1tm1.1(KOMP)Vlcg/Atp6v1b1tm1.1(KOMP)Vlcg
C57BL/6N-Atp6v1b1tm1.1(KOMP)Vlcg/Ucd
enlarged heart J:211773
increased circulating alanine transaminase level J:211773
Atp6v1b1tm1Choo/Atp6v1b1tm1Choo
involves: 129S1/Sv
abnormal olfactory system physiology J:192002
abnormal pH regulation J:192002
abnormal response to novel odor J:192002
Atp6v1b1tm1Choo/Atp6v1b1tm1Choo
involves: 129S1/Sv * C57BL/6
abnormal renal transport J:101414
abnormal urine calcium level J:101414
acidosis J:101414
decreased circulating bicarbonate level J:101414
decreased urine osmolality J:101414
normal hearing/vestibular/ear phenotype J:84744
increased urine pH J:101414
normal skeleton phenotype J:101414
Atp6v1b1vtx/Atp6v1b1vtx
B6.MRL-Atp6v1b1vtx/Kjn
decreased urine calcium level J:243701
normal hearing/vestibular/ear phenotype J:243701
increased urine pH J:243701
Atp6v1b1vtx/Atp6v1b1vtx
MRL/MpJ-Atp6v1b1vtx/Kjn
abnormal cochlea morphology J:243701
abnormal cochlear endolymph ionic homeostasis J:243701
abnormal membranous labyrinth morphology J:243701
abnormal organ of Corti morphology J:243701
abnormal Reissner membrane morphology J:243701
abnormal spiral ligament fibrocyte morphology J:243701
abnormal spiral limbus morphology J:243701
abnormal type I spiral ligament fibrocytes J:243701
abnormal type III spiral ligament fibrocytes J:243701
bidirectional circling J:243701
decreased cochlear outer hair cell number J:243701
decreased endocochlear potential J:243701
decreased otolith number J:243701
decreased urine calcium level J:243701
dilated endolymphatic duct J:243701
dilated scala media J:243701
head tilt J:243701
increased or absent threshold for auditory brainstem response J:243701
small scala tympani J:243701
thin spiral ligament J:243701

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory