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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Phc1
polyhomeotic 1
MGI:103248
56 phenotypes from 2 alleles in 3 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Phc1tm1Os/Phc1tm1Os
involves: 129/Sv * C57BL/6
abnormal occipital bone morphology J:100027
abnormal presphenoid bone morphology J:100027
abnormal sphenoid bone morphology J:100027
abnormal vertebrae morphology J:100027
cleft secondary palate J:100027
perinatal lethality, complete penetrance J:100027
Phc1tm1Os/Phc1tm1Os
involves: 129S2/SvPas * C57BL/6
abnormal B cell differentiation J:75707
abnormal bulbus cordis morphology J:78065
abnormal cardiac outflow tract development J:78065
abnormal cardiovascular development J:78065
abnormal heart looping J:78065
abnormal heart morphology J:43764
abnormal heart right ventricle outflow tract morphology J:43764
abnormal hematopoietic stem cell morphology J:75707
abnormal optic cup morphology J:43764
abnormal semilunar valve morphology J:43764
abnormal sternum morphology J:43764
abnormal vertebrae morphology J:43764
aortic valve stenosis J:43764
cervical vertebral fusion J:43764
cervical vertebral transformation J:43764
cleft secondary palate J:43764
decreased body size J:43764
decreased spleen weight J:43764
decreased thymus weight J:43764
dilated heart ventricle J:43764
extramedullary hematopoiesis J:75707
heart right ventricle hypertrophy J:43764
impaired hematopoiesis J:75707
lumbar vertebral transformation J:43764
overriding aortic valve J:43764
palatal shelves fail to meet at midline J:43764
parathyroid hypoplasia J:43764
perinatal lethality, complete penetrance J:43764
pulmonary trunk hypoplasia J:43764
pulmonary valve stenosis J:43764
small occipital bone J:43764
thin ventricular wall J:43764
ventricular septal defect J:43764
Phc1tm1Os/Phc1tm1Os
Tg(Myh7-Phc1)#Yota/0
involves: 129S2/SvPas * C57BL/6
abnormal cardiovascular system morphology J:75968
abnormal heart morphology J:75968
atrial septal defect J:75968
ventricular septal defect J:75968
Tg(Myh7-Phc1)#Yota/0
involves: C57BL/6
abnormal atrial thrombosis J:75968
abnormal M line morphology J:75968
abnormal mitochondrial crista morphology J:75968
abnormal mitochondrial shape J:75968
abnormal myocardial fiber morphology J:75968
abnormal sarcomere morphology J:75968
abnormal Z line morphology J:75968
ascites J:75968
congestive heart failure J:75968
decreased ventricle muscle contractility J:75968
dilated cardiomyopathy J:75968
edema J:75968
enlarged heart J:75968
increased cardiomyocyte apoptosis J:75968
pleural effusion J:75968
premature death J:75968
respiratory distress J:75968
thin myocardium J:75968

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory