Ptgdr Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ptgdr
prostaglandin D receptor
MGI:102966

18 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ptgdr^tm1Dgen/Ptgdr⁺ B6.129P2-Ptgdr^tm1Dgen	decreased vasodilation	J:109107
Ptgdr^tm1Dgen/Ptgdr⁺ B6.129P2-Ptgdr^tm1Dgen	increased vasodilation	J:109107
Ptgdr^tm1Dgen/Ptgdr^tm1Dgen B6.129P2-Ptgdr^tm1Dgen	decreased vasodilation	J:109107
Ptgdr^tm1Sna/Ptgdr^tm1Sna B6.129P2-Ptgdr^tm1Sna/Sna	abnormal dermal mast cell morphology	J:197334
	abnormal mast cell physiology	J:197334
	abnormal vascular permeability	J:197334
	decreased mast cell degranulation	J:197334
	decreased mast cell histamine storage	J:197334
	decreased susceptibility to type I hypersensitivity reaction	J:197334
Ptgdr^tm1Sna/Ptgdr^tm1Sna involves: 129P2/OlaHsd * C57BL/6	abnormal macrophage activation involved in immune response	J:243958
	brain inflammation	J:243958
	decreased microglial cell activation	J:243958
	increased CD4-positive, alpha-beta T cell number	J:243958
	increased interleukin-1 beta secretion	J:243958
	increased regulatory T cell number	J:243958
	increased susceptibility to Coronaviridae infection	J:243958
	increased susceptibility to Coronaviridae infection induced morbidity/mortality	J:243958
	respiratory system inflammation	J:61023
	spongiform encephalopathy	J:243958

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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