Pcsk6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pcsk6
proprotein convertase subtilisin/kexin type 6
MGI:102897

31 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pcsk6^em1(IMPC)J/Pcsk6^em1(IMPC)J C57BL/6NJ-Pcsk6^em1(IMPC)J/Mmjax	abnormal optic disk morphology	J:211773
	cataract	J:211773
	corneal opacity	J:211773
	irregularly shaped pupil	J:211773
Pcsk6^tm1Rob/Pcsk6^tm1Rob involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal direction of heart looping	J:62181
	abnormal estrous cycle	J:180839
	abnormal female reproductive system physiology	J:180839
	abnormal left-right axis patterning	J:62181
	abnormal nervous system morphology	J:62181
	abnormal ovary morphology	J:180839
	absent embryonic telencephalon	J:62181
	absent nasal capsule	J:62181
	absent ovarian follicles	J:180839
	agnathia	J:62181
	anophthalmia	J:180839
	common atrium	J:62181
	common ventricle	J:62181
	cyclopia	J:62181
	decreased tumor latency	J:180839
	dextrocardia	J:62181
	double outlet right ventricle	J:62181
	early reproductive senescence	J:180839
	fused first pharyngeal arch	J:62181
	increased ovary tumor incidence	J:180839
	increased reproductive system tumor incidence	J:180839
	left pulmonary isomerism	J:62181
	lethality throughout fetal growth and development, incomplete penetrance	J:62181
	ovary cyst	J:180839
	persistent truncus arteriosus	J:62181
	truncated foregut	J:62181
	ventricular septal defect	J:62181

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23