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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Guca1a
guanylate cyclase activator 1a (retina)
MGI:102770
13 phenotypes from 5 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Guca1a/Guca1btm1Jnc/Guca1a+
involves: 129S1/Sv * C57BL/6
abnormal eye electrophysiology J:83914
Guca1a/Guca1btm1Jnc/Guca1a/Guca1btm1Jnc
involves: 129S1/Sv * C57BL/6
abnormal rod electrophysiology J:83914, J:166744
Guca1atm1.1Hunt/Guca1a+
involves: 129
abnormal cone electrophysiology J:171667
abnormal eye electrophysiology J:171667
abnormal rod electrophysiology J:171667
decreased retinal cone cell number J:171667
decreased retinal photoreceptor cell number J:171667
retinal photoreceptor degeneration J:171667
short photoreceptor outer segment J:171667
thin retinal outer nuclear layer J:171667
Guca1atm1.1Hunt/Guca1atm1.1Hunt
involves: 129
abnormal cone electrophysiology J:171667
abnormal eye electrophysiology J:171667
abnormal rod electrophysiology J:171667
decreased retinal cone cell number J:171667
decreased retinal photoreceptor cell number J:171667
retinal photoreceptor degeneration J:171667
short photoreceptor outer segment J:171667
thin retinal outer nuclear layer J:171667
Guca1atm1Itl/Guca1atm1Itl
involves: 129S6/SvEvTac * C57BL/6NTac
abnormal photoreceptor outer segment morphology J:192199
abnormal retina morphology J:192199
abnormal rod electrophysiology J:192199
Tg(Guca1a*L151F)#Wbae/0
involves: C57BL/6J * FVB/N
decreased a wave amplitude J:199392
decreased b wave amplitude J:199392
decreased visual acuity J:199392
retinal photoreceptor degeneration J:199392
thin retinal outer nuclear layer J:199392
Tg(Guca1a*L151F/EGFP)#Wbae/0
involves: C57BL/6J * FVB/N
decreased a wave amplitude J:199392
decreased b wave amplitude J:199392
decreased visual acuity J:199392
retinal photoreceptor degeneration J:199392
thin retinal outer nuclear layer J:199392

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory