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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Itga7
integrin alpha 7
MGI:102700
26 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Itga7tm1Burk/Itga7tm1Burk
involves: 129S1/Sv * 129X1/SvJ
abnormal diaphragm morphology J:187752
abnormal muscle physiology J:187752
abnormal skeletal muscle fiber type ratio J:187752
centrally nucleated skeletal muscle fibers J:187752
embryonic lethality, incomplete penetrance J:187752
kyphosis J:187752
myopathy J:187752
premature death J:187752
skeletal muscle necrosis J:187752
Itga7tm1Burk/Itga7tm1Burk
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
abnormal blood vessel morphology J:100236
abnormal vascular smooth muscle morphology J:100236
hemorrhage J:100236
intracranial hemorrhage J:100236
myopathy J:100236
prenatal lethality, incomplete penetrance J:100236
vascular smooth muscle hyperplasia J:100236
vascular smooth muscle hypertrophy J:100236
Itga7tm1Umr/Itga7tm1Umr
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal diaphragm morphology J:43840
abnormal Schwann cell physiology J:204174
abnormal skeletal muscle morphology J:43840, J:82116
abnormal soleus morphology J:43840
centrally nucleated skeletal muscle fibers J:43840
dystrophic muscle J:43840
embryonic lethality during organogenesis, incomplete penetrance J:43840
increased circulating creatine kinase level J:43840
increased skeletal muscle fiber size J:43840
increased variability of skeletal muscle fiber size J:43840
muscle degeneration J:43840
skeletal muscle fiber atrophy J:43840

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory