Akr1b7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Akr1b7
aldo-keto reductase family 1, member B7
MGI:101918

24 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Akr1b7^tm1.1Anm/Akr1b7^tm1.1Anm involves: 129	abnormal white adipose tissue physiology	J:208505
	normal behavior/neurological phenotype	J:208505
	decreased energy expenditure	J:208505
	decreased food intake	J:208505
	decreased respiratory quotient	J:208505
	hepatic steatosis	J:208505
	normal homeostasis/metabolism phenotype	J:208505
	increased body weight	J:208505
	increased circulating adiponectin level	J:208505
	increased circulating glycerol level	J:208505
	increased circulating insulin level	J:208505
	increased circulating leptin level	J:208505
	increased circulating triglyceride level	J:208505
	increased gonadal fat pad weight	J:208505
	increased inguinal fat pad weight	J:208505
	increased liver triglyceride level	J:208505
	increased liver weight	J:208505
	increased susceptibility to diet-induced obesity	J:208505
	increased white adipose tissue amount	J:208505
	increased white fat cell size	J:208505
	insulin resistance	J:208505
Akr1b7^tm1.1Fth/Akr1b7^tm1.1Fth involves: 129P2/OlaHsd * C57BL/6	decreased circulating progesterone level	J:123295
	increased circulating progesterone level	J:123295
	normal reproductive system phenotype	J:123295

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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