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Rfv1
QTL Detail
 Symbol
Name
ID
Rfv1
recovery from Friend virus 1
MGI:97905
Synonyms Rfv-1
Feature Type QTL
Genetic Map
Chromosome 17
cM position of peak correlated region/marker: Syntenic

Mapping data(3)
Alleles
and
phenotypes
 
This QTL controls susceptibility to splenomegaly induced by Friend leukemia virus. Susceptibility to splenomegaly and low recovery rate is associated with H2d haplotype in BALB/c and DBA/2; resistance and high recovery rate is associated with H2b haplotype in C57BL/6. Heterozygotes are intermediate.
 
Other database
links
Entrez Gene110101
References (Earliest) J:5058 Lilly F, The effect of histocompatibility-2 type on response to Friend leukemia virus in mice. J Exp Med. 1968 Mar 1;127(3):465-73
(Latest) J:34941 Pataer A, et al., Two dominant host resistance genes to pre-B lymphoma in wild-derived inbred mouse strain MSM/Ms. Cancer Res. 1996 Aug 15;56(16):3716-20
All references(8)
Other
accession IDs
MGD-MRK-13852, MGD-MRK-13855

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory