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Igh Complex/Cluster/Region Detail
Summary
  • Symbol
    Igh
  • Name
    immunoglobulin heavy chain complex
Location &
Maps
more
  • Sequence Map
    Chr12:113222388-115973574 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, Syntenic
  • Mapping Data
    26 experiments
Strain
Comparison
more
  • SNPs within 2kb
    43670 from dbSNP Build 142
  • PCR
    10
  • RFLP
    4
Human Diseases
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  • Mutations/Alleles
    5 with disease annotations
  • References
    5 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    78 phenotypes from 45 alleles in 32 genetic backgrounds
    116 phenotypes from multigenic genotypes
    517 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit abnormal B cell morphology and physiology.
Sequences &
Gene Models
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  • All Sequences
    2
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 111507 NCBI Gene Model | MGI Sequence Detail 2751187 C57BL/6J ±  kb
For the selected sequence
Molecular
Reagents
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  • All nucleic 11
    Genomic 2
    cDNA 2
    Primer pair 6
    Other 1
Other
Accession IDs
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MGD-MRK-11239
References
more
  • Summaries
    All 657
    Diseases 5
    Phenotypes 517
  • Earliest
    J:284952 Bosma MJ, et al., Congenic mouse strains: the expression of a hidden immunoglobulin allotype in a congenic partner strain of BALB-c mice. J Exp Med. 1974;139(3):512-27
  • Latest
    J:347041 Zhu F, et al., Spatiotemporal resolution of germinal center Tfh cell differentiation and divergence from central memory CD4(+) T cell fate. Nat Commun. 2023 Jun 17;14(1):3611
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory