GO Annotations Graph

• Symbol: Drd1
• Name: dopamine receptor D1
• ID: MGI:99578

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031701	angiotensin receptor binding	ISO	J:155856
Molecular Function	GO:0051117	ATPase binding	ISO	J:155856
Molecular Function	GO:0031750	D3 dopamine receptor binding	ISO	J:155856
Molecular Function	GO:0035240	dopamine binding	ISO	J:155856
Molecular Function	GO:0035240	dopamine binding	ISO	J:164563
Molecular Function	GO:0004952	dopamine neurotransmitter receptor activity	IDA	J:140050
Molecular Function	GO:0004952	dopamine neurotransmitter receptor activity	ISO	J:73065
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	ISO	J:155856
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	ISO	J:164563
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	IBA	J:265628
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	IDA	J:86377
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	IMP	J:22076
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	IMP	J:43604
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	IDA	J:65770
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	IDA	J:114543
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	IDA	J:29045
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	IDA	J:21603
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	IMP	J:100026
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	IDA	J:33119
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	IDA	J:16494
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	IDA	J:109223
Molecular Function	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	IDA	J:114543
Molecular Function	GO:0004930	G protein-coupled receptor activity	ISO	J:155856
Molecular Function	GO:0004930	G protein-coupled receptor activity	IBA	J:265628
Molecular Function	GO:0004930	G protein-coupled receptor activity	IDA	J:88364
Molecular Function	GO:0001965	G-protein alpha-subunit binding	ISO	J:155856
Molecular Function	GO:1901363	heterocyclic compound binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:224553
Molecular Function	GO:0005515	protein binding	IPI	J:235288
Molecular Function	GO:0005515	protein binding	IPI	J:235288
Molecular Function	GO:0005515	protein binding	IPI	J:261831
Molecular Function	GO:0005515	protein binding	IPI	J:38464
Molecular Function	GO:0005515	protein binding	IPI	J:211009
Molecular Function	GO:0005515	protein binding	IPI	J:38464
Molecular Function	GO:0019903	protein phosphatase binding	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:155856
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0005901	caveola	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0060170	ciliary membrane	ISO	J:164563
Cellular Component	GO:0005929	cilium	ISO	J:246963
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043198	dendritic shaft	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	IDA	J:224553
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0044327	dendritic spine head	ISO	J:155856
Cellular Component	GO:0044326	dendritic spine neck	ISO	J:155856
Cellular Component	GO:0012505	endomembrane system	IDA	J:211009
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:211009
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:232120
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:232120
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	EXP	J:263447
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263447
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:232120
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:232120
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:38464
Cellular Component	GO:0016020	membrane	IDA	J:22076
Cellular Component	GO:0016020	membrane	IDA	J:33119
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0097730	non-motile cilium	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:43604
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:211009
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:232120
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:232120
Cellular Component	GO:0098793	presynapse	IDA	J:200058
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:232120
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:232120
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0007190	activation of adenylate cyclase activity	ISO	J:164563
Biological Process	GO:0007190	activation of adenylate cyclase activity	IDA	J:81988
Biological Process	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	IDA	J:261831
Biological Process	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	IDA	J:33119
Biological Process	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	IMP	J:38464
Biological Process	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	IGI	J:79146
Biological Process	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	IDA	J:76004
Biological Process	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	IGI	J:119081
Biological Process	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	IDA	J:83301
Biological Process	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	IGI	J:119081
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007628	adult walking behavior	IGI	J:103886
Biological Process	GO:0007628	adult walking behavior	IMP	J:21603
Biological Process	GO:0007628	adult walking behavior	IGI	J:43791
Biological Process	GO:0007628	adult walking behavior	IGI	J:43791
Biological Process	GO:0008306	associative learning	ISO	J:155856
Biological Process	GO:0008306	associative learning	IMP	J:48769
Biological Process	GO:0014002	astrocyte development	IMP	J:120070
Biological Process	GO:0001662	behavioral fear response	IMP	J:67395
Biological Process	GO:0048148	behavioral response to cocaine	ISO	J:155856
Biological Process	GO:0048148	behavioral response to cocaine	IMP	J:121750
Biological Process	GO:0019722	calcium-mediated signaling	ISO	J:155856
Biological Process	GO:0016477	cell migration	IMP	J:121219
Biological Process	GO:0071870	cellular response to catecholamine stimulus	ISO	J:164563
Biological Process	GO:1903351	cellular response to dopamine	ISO	J:164563
Biological Process	GO:0021853	cerebral cortex GABAergic interneuron migration	IMP	J:121219
Biological Process	GO:0001661	conditioned taste aversion	IMP	J:101069
Biological Process	GO:0021542	dentate gyrus development	IMP	J:120070
Biological Process	GO:0007212	dopamine receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007212	dopamine receptor signaling pathway	IGI	J:109223
Biological Process	GO:0007212	dopamine receptor signaling pathway	IMP	J:112916
Biological Process	GO:0007212	dopamine receptor signaling pathway	IGI	J:109223
Biological Process	GO:0007212	dopamine receptor signaling pathway	IGI	J:77277
Biological Process	GO:0015872	dopamine transport	IMP	J:123805
Biological Process	GO:0042755	eating behavior	ISO	J:155856
Biological Process	GO:0007631	feeding behavior	IGI	J:91781
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IDA	J:88364
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IMP	J:123805
Biological Process	GO:0007187	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	ISO	J:164563
Biological Process	GO:0046323	glucose import	IMP	J:68124
Biological Process	GO:0007625	grooming behavior	ISO	J:155856
Biological Process	GO:0007625	grooming behavior	IMP	J:50990
Biological Process	GO:0007625	grooming behavior	IMP	J:56015
Biological Process	GO:0046959	habituation	IMP	J:97339
Biological Process	GO:0021766	hippocampus development	IMP	J:120070
Biological Process	GO:0006886	intracellular protein transport	ISO	J:155856
Biological Process	GO:0007612	learning	IMP	J:96505
Biological Process	GO:0007626	locomotory behavior	ISO	J:155856
Biological Process	GO:0007626	locomotory behavior	IGI	J:66955
Biological Process	GO:0007626	locomotory behavior	IMP	J:112986
Biological Process	GO:0007626	locomotory behavior	IMP	J:120070
Biological Process	GO:0007626	locomotory behavior	IGI	J:91781
Biological Process	GO:0007626	locomotory behavior	IMP	J:45740
Biological Process	GO:0007626	locomotory behavior	IGI	J:102600
Biological Process	GO:0007626	locomotory behavior	IMP	J:120070
Biological Process	GO:0007626	locomotory behavior	IMP	J:70445
Biological Process	GO:0007626	locomotory behavior	IMP	J:96505
Biological Process	GO:0007626	locomotory behavior	IMP	J:59146
Biological Process	GO:0007626	locomotory behavior	IMP	J:48769
Biological Process	GO:0007626	locomotory behavior	IMP	J:100026
Biological Process	GO:0007626	locomotory behavior	IMP	J:68124
Biological Process	GO:0060292	long-term synaptic depression	IMP	J:88654
Biological Process	GO:0060291	long-term synaptic potentiation	IMP	J:88654
Biological Process	GO:0060291	long-term synaptic potentiation	IMP	J:103731
Biological Process	GO:0060291	long-term synaptic potentiation	IMP	J:100026
Biological Process	GO:0042711	maternal behavior	IMP	J:120070
Biological Process	GO:0042711	maternal behavior	IMP	J:22076
Biological Process	GO:0007617	mating behavior	IDA	J:51133
Biological Process	GO:0007613	memory	IMP	J:102603
Biological Process	GO:0099010	modification of postsynaptic structure	EXP	J:263447
Biological Process	GO:0099010	modification of postsynaptic structure	IDA	J:263447
Biological Process	GO:0006936	muscle contraction	IMP	J:120070
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:155856
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:155856
Biological Process	GO:0042321	negative regulation of circadian sleep/wake cycle, sleep	ISO	J:155856
Biological Process	GO:0006469	negative regulation of protein kinase activity	ISO	J:155856
Biological Process	GO:0050805	negative regulation of synaptic transmission	ISO	J:155856
Biological Process	GO:0001764	neuron migration	IMP	J:121219
Biological Process	GO:0019228	neuronal action potential	IMP	J:112916
Biological Process	GO:0035106	operant conditioning	ISO	J:155856
Biological Process	GO:0035106	operant conditioning	IMP	J:107997
Biological Process	GO:0030432	peristalsis	IGI	J:91781
Biological Process	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway	IGI	J:119081
Biological Process	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway	IGI	J:119081
Biological Process	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway	IDA	J:107534
Biological Process	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway	ISO	J:73065
Biological Process	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway	IGI	J:119081
Biological Process	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	ISO	J:164563
Biological Process	GO:2000253	positive regulation of feeding behavior	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	ISO	J:155856
Biological Process	GO:0045838	positive regulation of membrane potential	ISO	J:155856
Biological Process	GO:2001224	positive regulation of neuron migration	IMP	J:121219
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	ISO	J:164563
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	IMP	J:35286
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	ISO	J:155856
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:200058
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	EXP	J:200058
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:200058
Biological Process	GO:0006606	protein import into nucleus	IMP	J:137074
Biological Process	GO:0006606	protein import into nucleus	EXP	J:137074
Biological Process	GO:0006468	protein phosphorylation	IDA	J:137074
Biological Process	GO:0042053	regulation of dopamine metabolic process	IMP	J:70177
Biological Process	GO:0043269	regulation of monoatomic ion transport	ISO	J:155856
Biological Process	GO:0001932	regulation of protein phosphorylation	IMP	J:137074
Biological Process	GO:0001932	regulation of protein phosphorylation	IMP	J:137074
Biological Process	GO:0019229	regulation of vasoconstriction	ISO	J:155856
Biological Process	GO:0001975	response to amphetamine	IMP	J:137069
Biological Process	GO:0001975	response to amphetamine	IMP	J:70445
Biological Process	GO:0001975	response to amphetamine	IGI	J:103950
Biological Process	GO:0001975	response to amphetamine	IGI	J:170830
Biological Process	GO:0001975	response to amphetamine	IGI	J:109223
Biological Process	GO:0001975	response to amphetamine	IMP	J:45740
Biological Process	GO:0001975	response to amphetamine	IGI	J:109223
Biological Process	GO:0001975	response to amphetamine	IMP	J:59146
Biological Process	GO:0001975	response to amphetamine	IMP	J:121750
Biological Process	GO:0042220	response to cocaine	IMP	J:43604
Biological Process	GO:0042220	response to cocaine	IMP	J:70445
Biological Process	GO:0042220	response to cocaine	IMP	J:59146
Biological Process	GO:0042220	response to cocaine	IMP	J:127798
Biological Process	GO:0042220	response to cocaine	IMP	J:126712
Biological Process	GO:0042220	response to cocaine	IMP	J:112916
Biological Process	GO:0009410	response to xenobiotic stimulus	IDA	J:30219
Biological Process	GO:0009410	response to xenobiotic stimulus	IMP	J:68124
Biological Process	GO:0046960	sensitization	IGI	J:103950
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0035176	social behavior	ISO	J:155856
Biological Process	GO:0021756	striatum development	IMP	J:120070
Biological Process	GO:0001963	synaptic transmission, dopaminergic	IMP	J:112916
Biological Process	GO:0035249	synaptic transmission, glutamatergic	IMP	J:35286
Biological Process	GO:0001659	temperature homeostasis	IMP	J:137069
Biological Process	GO:0019226	transmission of nerve impulse	IMP	J:84475
Biological Process	GO:0042311	vasodilation	IEA	J:72247
Biological Process	GO:0008542	visual learning	IMP	J:48769
Biological Process	GO:0008542	visual learning	IMP	J:102603
Biological Process	GO:0008542	visual learning	IMP	J:102600
Biological Process	GO:0008542	visual learning	IMP	J:96505