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GO Annotations Graph
Symbol
Name
ID
Xdh
xanthine dehydrogenase
MGI:98973

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:00515372 iron, 2 sulfur cluster bindingISOJ:155856
Molecular FunctionGO:00515372 iron, 2 sulfur cluster bindingISOJ:164563
Molecular FunctionGO:0003824catalytic activityIEAJ:72247
Molecular FunctionGO:0009055electron carrier activityIEAJ:72247
Molecular FunctionGO:0050660flavin adenine dinucleotide bindingISOJ:164563
Molecular FunctionGO:0050660flavin adenine dinucleotide bindingISOJ:155856
Molecular FunctionGO:0050660flavin adenine dinucleotide bindingIBAJ:161428
Molecular FunctionGO:0005506iron ion bindingIEAJ:72247
Molecular FunctionGO:0051536iron-sulfur cluster bindingIEAJ:72247
Molecular FunctionGO:0051536iron-sulfur cluster bindingIEAJ:60000
Molecular FunctionGO:0046872metal ion bindingIEAJ:72247
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0030151molybdenum ion bindingIEAJ:72247
Molecular FunctionGO:0043546molybdopterin cofactor bindingISOJ:164563
Molecular FunctionGO:0043546molybdopterin cofactor bindingISOJ:155856
Molecular FunctionGO:0016491oxidoreductase activityIDAJ:129870
Molecular FunctionGO:0016614oxidoreductase activity, acting on CH-OH group of donorsIEAJ:72247
Molecular FunctionGO:0016903oxidoreductase activity, acting on the aldehyde or oxo group of donorsIBAJ:161428
Molecular FunctionGO:0005515protein bindingIPIJ:30255
Molecular FunctionGO:0042803protein homodimerization activityISOJ:164563
Molecular FunctionGO:0004854xanthine dehydrogenase activityIDAJ:80993
Molecular FunctionGO:0004854xanthine dehydrogenase activityISOJ:155856
Molecular FunctionGO:0004854xanthine dehydrogenase activityISOJ:164563
Molecular FunctionGO:0004855xanthine oxidase activityISOJ:155856
Molecular FunctionGO:0004855xanthine oxidase activityISOJ:164563
Cellular ComponentGO:0005737cytoplasmIEAJ:60000
Cellular ComponentGO:0005829cytosolIBAJ:161428
Cellular ComponentGO:0005829cytosolISOJ:155856
Cellular ComponentGO:0005576extracellular regionIEAJ:60000
Cellular ComponentGO:0005615extracellular spaceIBAJ:161428
Cellular ComponentGO:0005615extracellular spaceISOJ:164563
Cellular ComponentGO:0005615extracellular spaceISOJ:155856
Cellular ComponentGO:0005777peroxisomeIEAJ:60000
Cellular ComponentGO:0016529sarcoplasmic reticulumIDAJ:217280
Biological ProcessGO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic processISOJ:164563
Biological ProcessGO:0045453bone resorptionISOJ:155856
Biological ProcessGO:0007595lactationIMPJ:80993
Biological ProcessGO:0045602negative regulation of endothelial cell differentiationISOJ:164563
Biological ProcessGO:0001937negative regulation of endothelial cell proliferationISOJ:164563
Biological ProcessGO:0010629negative regulation of gene expressionISOJ:164563
Biological ProcessGO:0051898negative regulation of protein kinase B signalingISOJ:164563
Biological ProcessGO:0001933negative regulation of protein phosphorylationISOJ:164563
Biological ProcessGO:1900747negative regulation of vascular endothelial growth factor signaling pathwayISOJ:164563
Biological ProcessGO:2001213negative regulation of vasculogenesisISOJ:164563
Biological ProcessGO:0055114oxidation-reduction processIDAJ:129870
Biological ProcessGO:1900745positive regulation of p38MAPK cascadeISOJ:164563
Biological ProcessGO:2000379positive regulation of reactive oxygen species metabolic processISOJ:164563
Biological ProcessGO:0030856regulation of epithelial cell differentiationIMPJ:80993
Biological ProcessGO:0010044response to aluminum ionISOJ:155856
Biological ProcessGO:0009115xanthine catabolic processISOJ:155856
Biological ProcessGO:0009115xanthine catabolic processISOJ:164563
Biological ProcessGO:0009115xanthine catabolic processIBAJ:161428


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/14/2021
MGI 6.17
The Jackson Laboratory