Wnt4 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Wnt4
wingless-type MMTV integration site family, member 4
MGI:98957

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005125	cytokine activity	IBA	J:265628
Molecular Function	GO:0005109	frizzled binding	IPI	J:164788
Molecular Function	GO:0005109	frizzled binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:123536
Molecular Function	GO:0005515	protein binding	IPI	J:51287
Molecular Function	GO:0005515	protein binding	IPI	J:63226
Molecular Function	GO:0005515	protein binding	IPI	J:75973
Molecular Function	GO:0048018	receptor ligand activity	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	TAS	J:52010
Molecular Function	GO:0003714	transcription corepressor activity	IDA	J:85499
Cellular Component	GO:0009986	cell surface	IDA	J:21428
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005788	endoplasmic reticulum lumen	TAS	Reactome:R-MMU-3238692
Cellular Component	GO:0031012	extracellular matrix	IDA	J:21428
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-3769366
Cellular Component	GO:0005615	extracellular space	IDA	J:196220
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Biological Process	GO:0048856	anatomical structure development	IGI	J:119030
Biological Process	GO:0097190	apoptotic signaling pathway	IGI	J:160549
Biological Process	GO:0097190	apoptotic signaling pathway	IGI	J:160549
Biological Process	GO:0097190	apoptotic signaling pathway	IGI	J:160549
Biological Process	GO:0097190	apoptotic signaling pathway	IGI	J:160549
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IMP	J:100575
Biological Process	GO:0048754	branching morphogenesis of an epithelial tube	IGI	J:76225
Biological Process	GO:0060070	canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:210448
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:164788
Biological Process	GO:0060070	canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:67003
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:160549
Biological Process	GO:0030154	cell differentiation	IMP	J:106304
Biological Process	GO:0045165	cell fate commitment	IBA	J:265628
Biological Process	GO:0045165	cell fate commitment	IMP	J:132979
Biological Process	GO:0007267	cell-cell signaling	TAS	J:52010
Biological Process	GO:0009267	cellular response to starvation	IEP	J:193325
Biological Process	GO:0001838	embryonic epithelial tube formation	IDA	J:108713
Biological Process	GO:0008585	female gonad development	IMP	J:90277
Biological Process	GO:0008585	female gonad development	IMP	J:154784
Biological Process	GO:0008585	female gonad development	IMP	J:158526
Biological Process	GO:0030237	female sex determination	ISO	J:164563
Biological Process	GO:0030237	female sex determination	ISS	J:163146
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:110252
Biological Process	GO:0007276	gamete generation	IGI	J:90277
Biological Process	GO:0042445	hormone metabolic process	IMP	J:80420
Biological Process	GO:0033080	immature T cell proliferation in thymus	IMP	J:137842
Biological Process	GO:0060993	kidney morphogenesis	IGI	J:194051
Biological Process	GO:0008584	male gonad development	ISS	J:163146
Biological Process	GO:0008584	male gonad development	ISO	J:164563
Biological Process	GO:0008584	male gonad development	IMP	J:106304
Biological Process	GO:0140013	meiotic nuclear division	IGI	J:158526
Biological Process	GO:0140013	meiotic nuclear division	IGI	J:158526
Biological Process	GO:0060231	mesenchymal to epithelial transition	IMP	J:171469
Biological Process	GO:0060231	mesenchymal to epithelial transition	IMP	J:21884
Biological Process	GO:0072164	mesonephric tubule development	IGI	J:157251
Biological Process	GO:0001823	mesonephros development	IMP	J:133086
Biological Process	GO:0072162	metanephric mesenchymal cell differentiation	NAS	J:112694
Biological Process	GO:0072210	metanephric nephron development	IMP	J:133949
Biological Process	GO:0072273	metanephric nephron morphogenesis	IMP	J:154784
Biological Process	GO:0072174	metanephric tubule formation	IMP	J:171512
Biological Process	GO:0001656	metanephros development	IMP	J:21884
Biological Process	GO:0001656	metanephros development	TAS	J:52010
Biological Process	GO:0007275	multicellular organism development	IEA	J:72247
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:2000180	negative regulation of androgen biosynthetic process	ISO	J:164563
Biological Process	GO:2001234	negative regulation of apoptotic signaling pathway	IGI	J:160549
Biological Process	GO:2001234	negative regulation of apoptotic signaling pathway	IGI	J:160549
Biological Process	GO:0045596	negative regulation of cell differentiation	IMP	J:106304
Biological Process	GO:0030336	negative regulation of cell migration	IGI	J:196220
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:147038
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:85499
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISS	J:85499
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	IGI	J:110252
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:76225
Biological Process	GO:2000019	negative regulation of male gonad development	ISO	J:164563
Biological Process	GO:0010894	negative regulation of steroid biosynthetic process	ISO	J:164563
Biological Process	GO:0061369	negative regulation of testicular blood vessel morphogenesis	ISO	J:164563
Biological Process	GO:2000225	negative regulation of testosterone biosynthetic process	ISO	J:164563
Biological Process	GO:2000225	negative regulation of testosterone biosynthetic process	IMP	J:85499
Biological Process	GO:0061045	negative regulation of wound healing	IGI	J:196220
Biological Process	GO:0072006	nephron development	IMP	J:171469
Biological Process	GO:0030182	neuron differentiation	IBA	J:265628
Biological Process	GO:0035567	non-canonical Wnt signaling pathway	IDA	J:137842
Biological Process	GO:0038030	non-canonical Wnt signaling pathway via MAPK cascade	ISO	J:164563
Biological Process	GO:0048599	oocyte development	IMP	J:52554
Biological Process	GO:0048599	oocyte development	IGI	J:160549
Biological Process	GO:0048599	oocyte development	IGI	J:160549
Biological Process	GO:0061205	paramesonephric duct development	ISO	J:164563
Biological Process	GO:0061205	paramesonephric duct development	IMP	J:133086
Biological Process	GO:0061205	paramesonephric duct development	IMP	J:154784
Biological Process	GO:1904238	pericyte cell differentiation	IMP	J:108713
Biological Process	GO:1904238	pericyte cell differentiation	IDA	J:108713
Biological Process	GO:0032349	positive regulation of aldosterone biosynthetic process	ISO	J:164563
Biological Process	GO:0030501	positive regulation of bone mineralization	ISO	J:164563
Biological Process	GO:0032967	positive regulation of collagen biosynthetic process	ISO	J:164563
Biological Process	GO:2000066	positive regulation of cortisol biosynthetic process	ISO	J:164563
Biological Process	GO:0061184	positive regulation of dermatome development	ISS	J:53153
Biological Process	GO:0061184	positive regulation of dermatome development	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:163146
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:147038
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:44227
Biological Process	GO:0051894	positive regulation of focal adhesion assembly	IGI	J:196220
Biological Process	GO:0043547	positive regulation of GTPase activity	IGI	J:196220
Biological Process	GO:0045836	positive regulation of meiotic nuclear division	IGI	J:158526
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	ISO	J:164563
Biological Process	GO:0051496	positive regulation of stress fiber assembly	IGI	J:196220
Biological Process	GO:0022407	regulation of cell-cell adhesion	IMP	J:158526
Biological Process	GO:0072033	renal vesicle formation	IMP	J:100575
Biological Process	GO:0072034	renal vesicle induction	IDA	J:71476
Biological Process	GO:0060008	Sertoli cell differentiation	IMP	J:106304
Biological Process	GO:0007548	sex differentiation	IMP	J:52554
Biological Process	GO:0007165	signal transduction	TAS	J:52010
Biological Process	GO:0051145	smooth muscle cell differentiation	IDA	J:108713
Biological Process	GO:0051145	smooth muscle cell differentiation	IDA	J:108713
Biological Process	GO:0051145	smooth muscle cell differentiation	IMP	J:108713
Biological Process	GO:0051145	smooth muscle cell differentiation	IMP	J:108713
Biological Process	GO:0060126	somatotropin secreting cell differentiation	IMP	J:132979
Biological Process	GO:0033077	T cell differentiation in thymus	IDA	J:67003
Biological Process	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis	IMP	J:61384
Biological Process	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation	IMP	J:132979
Biological Process	GO:0035239	tube morphogenesis	IMP	J:108713
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:72247

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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