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GO Annotations Graph
Symbol
Name
ID
Tek
TEK receptor tyrosine kinase
MGI:98664

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0019838growth factor bindingISOJ:155856
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:46939
Molecular FunctionGO:0005515protein bindingIPIJ:155217
Molecular FunctionGO:0005515protein bindingIPIJ:200516
Molecular FunctionGO:0005515protein bindingIPIJ:157867
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0004713protein tyrosine kinase activityISOJ:164563
Molecular FunctionGO:0004713protein tyrosine kinase activityIDAJ:20015
Molecular FunctionGO:0004872receptor activityIPIJ:37460
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Molecular FunctionGO:0004714transmembrane receptor protein tyrosine kinase activityIEAJ:72245
Molecular FunctionGO:0004714transmembrane receptor protein tyrosine kinase activityIEAJ:72247
Cellular ComponentGO:0005884colocalizes_with
actin filament
ISOJ:164563
Cellular ComponentGO:0016324apical plasma membraneISOJ:164563
Cellular ComponentGO:0009925basal plasma membraneISOJ:164563
Cellular ComponentGO:0016323basolateral plasma membraneISOJ:164563
Cellular ComponentGO:0030054cell junctionIEAJ:60000
Cellular ComponentGO:0009986cell surfaceISOJ:164563
Cellular ComponentGO:0005911cell-cell junctionISOJ:164563
Cellular ComponentGO:0005737cytoplasmIEAJ:60000
Cellular ComponentGO:0005856cytoskeletonIEAJ:60000
Cellular ComponentGO:0005576extracellular regionIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneISMJ:15180
Cellular ComponentGO:0005887integral component of plasma membraneISOJ:164563
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0045121membrane raftISOJ:164563
Cellular ComponentGO:0005902microvillusISOJ:164563
Cellular ComponentGO:0048471perinuclear region of cytoplasmIDAJ:157867
Cellular ComponentGO:0005886plasma membraneIEAJ:60000
Cellular ComponentGO:0001725colocalizes_with
stress fiber
ISOJ:164563
Biological ProcessGO:0001525angiogenesisTASJ:169941
Biological ProcessGO:0001525angiogenesisIMPJ:26844
Biological ProcessGO:0001525angiogenesisIMPJ:51336
Biological ProcessGO:0007160cell-matrix adhesionIMPJ:79305
Biological ProcessGO:0001935endothelial cell proliferationIMPJ:20015
Biological ProcessGO:0007507heart developmentIMPJ:20015
Biological ProcessGO:0060347heart trabecula formationIMPJ:20015
Biological ProcessGO:0030097hemopoiesisIMPJ:91951
Biological ProcessGO:0030097hemopoiesisIMPJ:51336
Biological ProcessGO:0035556intracellular signal transductionISOJ:155856
Biological ProcessGO:0016525negative regulation of angiogenesisISOJ:164563
Biological ProcessGO:0043066negative regulation of apoptotic processIGIJ:149670
Biological ProcessGO:2000352negative regulation of endothelial cell apoptotic processIMPJ:115217
Biological ProcessGO:0001569patterning of blood vesselsTASJ:169941
Biological ProcessGO:0018108peptidyl-tyrosine phosphorylationISOJ:164563
Biological ProcessGO:0018108peptidyl-tyrosine phosphorylationIDAJ:20015
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:2000251positive regulation of actin cytoskeleton reorganizationISOJ:164563
Biological ProcessGO:0045766positive regulation of angiogenesisISOJ:164563
Biological ProcessGO:0045766positive regulation of angiogenesisISOJ:155856
Biological ProcessGO:0045785positive regulation of cell adhesionIMPJ:91951
Biological ProcessGO:0002741positive regulation of cytokine secretion involved in immune responseIDAJ:157867
Biological ProcessGO:0010595positive regulation of endothelial cell migrationTASJ:164086
Biological ProcessGO:0010595positive regulation of endothelial cell migrationISOJ:164563
Biological ProcessGO:0010595positive regulation of endothelial cell migrationTASJ:169941
Biological ProcessGO:0070374positive regulation of ERK1 and ERK2 cascadeISOJ:164563
Biological ProcessGO:0051894positive regulation of focal adhesion assemblyISOJ:164563
Biological ProcessGO:1902533positive regulation of intracellular signal transductionISOJ:164563
Biological ProcessGO:0033138positive regulation of peptidyl-serine phosphorylationIGIJ:149670
Biological ProcessGO:0043552positive regulation of phosphatidylinositol 3-kinase activityISOJ:164563
Biological ProcessGO:0014068positive regulation of phosphatidylinositol 3-kinase signalingISOJ:164563
Biological ProcessGO:0042307positive regulation of protein import into nucleusIDAJ:157867
Biological ProcessGO:0051897positive regulation of protein kinase B signalingISOJ:164563
Biological ProcessGO:0001934positive regulation of protein phosphorylationIDAJ:157867
Biological ProcessGO:0001934positive regulation of protein phosphorylationISOJ:164563
Biological ProcessGO:0030949positive regulation of vascular endothelial growth factor receptor signaling pathwayTASJ:164086
Biological ProcessGO:0046777protein autophosphorylationISOJ:164563
Biological ProcessGO:0051259protein oligomerizationISOJ:164563
Biological ProcessGO:0006468protein phosphorylationIEAJ:72247
Biological ProcessGO:0045765regulation of angiogenesisIMPJ:79305
Biological ProcessGO:0030334regulation of cell migrationIDAJ:157867
Biological ProcessGO:0030334regulation of cell migrationIMPJ:79305
Biological ProcessGO:0001936regulation of endothelial cell proliferationTASJ:164086
Biological ProcessGO:0032878regulation of establishment or maintenance of cell polarityISOJ:164563
Biological ProcessGO:1901222regulation of NIK/NF-kappaB signalingIGIJ:157867
Biological ProcessGO:0043627response to estrogenISOJ:155856
Biological ProcessGO:0032526response to retinoic acidIDAJ:137480
Biological ProcessGO:0016337single organismal cell-cell adhesionIMPJ:79305
Biological ProcessGO:0002040sprouting angiogenesisISOJ:164563
Biological ProcessGO:0034446substrate adhesion-dependent cell spreadingISOJ:164563
Biological ProcessGO:0048014Tie signaling pathwayISOJ:164563
Biological ProcessGO:0048014Tie signaling pathwayTASJ:169941
Biological ProcessGO:0007169transmembrane receptor protein tyrosine kinase signaling pathwayISOJ:164563
Biological ProcessGO:0001570vasculogenesisIMPJ:20015


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/10/2020
MGI 6.16
The Jackson Laboratory