GO Annotations Graph

• Symbol: Ptpn5
• Name: protein tyrosine phosphatase, non-receptor type 5
• ID: MGI:97807

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035254	glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0051019	mitogen-activated protein kinase binding	ISO	J:155856
Molecular Function	GO:0016791	phosphatase activity	IEA	J:72247
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IEA	J:60000
Molecular Function	GO:0001784	phosphotyrosine residue binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:245292
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0019901	protein kinase binding	IBA	J:265628
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	ISO	J:155856
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	IBA	J:265628
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	IMP	J:101438
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030054	cell junction	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:1990635	proximal dendrite	ISO	J:155856
Cellular Component	GO:0097060	synaptic membrane	ISO	J:155856
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Biological Process	GO:0016311	dephosphorylation	IEA	J:72247
Biological Process	GO:0035640	exploration behavior	ISO	J:155856
Biological Process	GO:0043407	negative regulation of MAP kinase activity	ISO	J:155856
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	ISO	J:155856
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	IBA	J:265628
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	ISO	J:155856
Biological Process	GO:1901216	positive regulation of neuron death	ISO	J:155856
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0042307	positive regulation of protein import into nucleus	ISO	J:155856
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:1903955	positive regulation of protein targeting to mitochondrion	ISO	J:155856
Biological Process	GO:0002092	positive regulation of receptor internalization	ISO	J:155856
Biological Process	GO:2001025	positive regulation of response to drug	ISO	J:155856
Biological Process	GO:0006470	protein dephosphorylation	IMP	J:101438
Biological Process	GO:0035902	response to immobilization stress	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IBA	J:265628