GO Annotations Graph

• Symbol: Plaur
• Name: plasminogen activator, urokinase receptor
• ID: MGI:97612

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:155175
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0030377	urokinase plasminogen activator receptor activity	IEA	J:72247
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:157880
Cellular Component	GO:0098637	protein complex involved in cell-matrix adhesion	ISO	J:164563
Cellular Component	GO:1905370	serine-type endopeptidase complex	ISO	J:164563
Cellular Component	GO:1905370	serine-type endopeptidase complex	IPI	J:165944
Biological Process	GO:0060742	epithelial cell differentiation involved in prostate gland development	ISO	J:155856
Biological Process	GO:0048762	mesenchymal cell differentiation	ISO	J:155856
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0043388	positive regulation of DNA binding	ISO	J:164563
Biological Process	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0034112	positive regulation of homotypic cell-cell adhesion	ISO	J:164563
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	ISO	J:164563
Biological Process	GO:0030155	regulation of cell adhesion	ISO	J:164563
Biological Process	GO:0051917	regulation of fibrinolysis	NAS	J:320117
Biological Process	GO:0010755	regulation of plasminogen activation	NAS	J:320117
Biological Process	GO:0030162	regulation of proteolysis	IEA	J:72247
Biological Process	GO:0038195	urokinase plasminogen activator signaling pathway	NAS	J:320117