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GO Annotations Graph
Symbol
Name
ID
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
MGI:97385

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0005004GPI-linked ephrin receptor activityISOJ:155856
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0005030neurotrophin receptor activityISOJ:164563
Molecular FunctionGO:0005030neurotrophin receptor activityISOJ:155856
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0002039p53 bindingISOJ:164563
Molecular FunctionGO:0005515protein bindingIPIJ:201759
Molecular FunctionGO:0005515protein bindingIPIJ:72304
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0004713protein tyrosine kinase activityIEAJ:60000
Molecular FunctionGO:0004713protein tyrosine kinase activityIEAJ:72247
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Molecular FunctionGO:0004714transmembrane receptor protein tyrosine kinase activityIEAJ:72247
Molecular FunctionGO:0004714transmembrane receptor protein tyrosine kinase activityIEAJ:72245
Cellular ComponentGO:0005737cytoplasmIDAJ:54178
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0005887integral component of plasma membraneIEAJ:72247
Cellular ComponentGO:0016020membraneISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:155856
Cellular ComponentGO:0043235receptor complexISOJ:194542
Biological ProcessGO:0090630activation of GTPase activityISOJ:164563
Biological ProcessGO:0000187activation of MAPK activityISOJ:164563
Biological ProcessGO:0032148activation of protein kinase B activityISOJ:164563
Biological ProcessGO:0030154cell differentiationIEAJ:60000
Biological ProcessGO:0048013ephrin receptor signaling pathwayISOJ:155856
Biological ProcessGO:0007507heart developmentISOJ:164563
Biological ProcessGO:0070306lens fiber cell differentiationIGIJ:189960
Biological ProcessGO:0042490mechanoreceptor differentiationIMPJ:93853
Biological ProcessGO:0007275multicellular organism developmentIEAJ:60000
Biological ProcessGO:0048712negative regulation of astrocyte differentiationISOJ:155856
Biological ProcessGO:0060548negative regulation of cell deathISOJ:155856
Biological ProcessGO:0001933negative regulation of protein phosphorylationISOJ:164563
Biological ProcessGO:0007399nervous system developmentIEAJ:60000
Biological ProcessGO:0048665neuron fate specificationISOJ:155856
Biological ProcessGO:0001764neuron migrationISOJ:155856
Biological ProcessGO:0038179neurotrophin signaling pathwayISOJ:155856
Biological ProcessGO:0038179neurotrophin signaling pathwayISOJ:164563
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:2000251positive regulation of actin cytoskeleton reorganizationISOJ:164563
Biological ProcessGO:0043065positive regulation of apoptotic processIDAJ:201759
Biological ProcessGO:0048691positive regulation of axon extension involved in regenerationIGIJ:101705
Biological ProcessGO:0030335positive regulation of cell migrationISOJ:164563
Biological ProcessGO:0008284positive regulation of cell proliferationISOJ:164563
Biological ProcessGO:0010628positive regulation of gene expressionISOJ:164563
Biological ProcessGO:0033138positive regulation of peptidyl-serine phosphorylationISOJ:164563
Biological ProcessGO:0050927positive regulation of positive chemotaxisISOJ:164563
Biological ProcessGO:0051965positive regulation of synapse assemblyIDAJ:211830
Biological ProcessGO:0046777protein autophosphorylationISOJ:155856
Biological ProcessGO:0006468protein phosphorylationIEAJ:72247
Biological ProcessGO:0007169transmembrane receptor protein tyrosine kinase signaling pathwayISOJ:164563


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/09/2022
MGI 6.21
The Jackson Laboratory