GO Annotations Graph

• Symbol: Lrpap1
• Name: low density lipoprotein receptor-related protein associated protein 1
• ID: MGI:96829

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008201	heparin binding	IEA	J:60000
Molecular Function	GO:0008201	heparin binding	IEA	J:72247
Molecular Function	GO:0035473	lipase binding	ISO	J:155856
Molecular Function	GO:0035473	lipase binding	IBA	J:265628
Molecular Function	GO:0050750	low-density lipoprotein particle receptor binding	ISO	J:164563
Molecular Function	GO:0050750	low-density lipoprotein particle receptor binding	IBA	J:265628
Molecular Function	GO:0050750	low-density lipoprotein particle receptor binding	IPI	J:90197
Molecular Function	GO:0050750	low-density lipoprotein particle receptor binding	ISO	J:103781
Molecular Function	GO:0050750	low-density lipoprotein particle receptor binding	IPI	J:102174
Molecular Function	GO:0048019	receptor antagonist activity	ISO	J:164563
Molecular Function	GO:0048019	receptor antagonist activity	IBA	J:265628
Molecular Function	GO:0048018	receptor ligand activity	ISO	J:164563
Molecular Function	GO:0070326	very-low-density lipoprotein particle receptor binding	ISO	J:164563
Molecular Function	GO:0070326	very-low-density lipoprotein particle receptor binding	IBA	J:265628
Cellular Component	GO:0005801	cis-Golgi network	ISO	J:164563
Cellular Component	GO:0005801	cis-Golgi network	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0012505	endomembrane system	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	ISO	J:164563
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	IBA	J:265628
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0005768	endosome	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:103781
Cellular Component	GO:0005791	rough endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0048237	rough endoplasmic reticulum lumen	ISO	J:164563
Cellular Component	GO:0048237	rough endoplasmic reticulum lumen	ISO	J:155856
Cellular Component	GO:0048237	rough endoplasmic reticulum lumen	IBA	J:265628
Cellular Component	GO:0031982	vesicle	ISO	J:155856
Biological Process	GO:0150093	amyloid-beta clearance by transcytosis	ISO	J:164563
Biological Process	GO:1900222	negative regulation of amyloid-beta clearance	ISO	J:164563
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:164563
Biological Process	GO:0032091	negative regulation of protein binding	ISO	J:164563
Biological Process	GO:0002091	negative regulation of receptor internalization	ISO	J:164563
Biological Process	GO:0002091	negative regulation of receptor internalization	IBA	J:265628
Biological Process	GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	ISO	J:164563
Biological Process	GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	IBA	J:265628
Biological Process	GO:0048259	regulation of receptor-mediated endocytosis	ISO	J:164563
Biological Process	GO:0007165	signal transduction	ISO	J:164563