GO Annotations Graph

• Symbol: Kcna2
• Name: potassium voltage-gated channel, shaker-related subfamily, member 2
• ID: MGI:96659

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	ISO	J:155856
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	IBA	J:265628
Molecular Function	GO:0019894	kinesin binding	ISO	J:155856
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0015271	outward rectifier potassium channel activity	ISO	J:155856
Molecular Function	GO:0005267	potassium channel activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:197477
Molecular Function	GO:0005515	protein binding	IPI	J:197477
Molecular Function	GO:0005515	protein binding	IPI	J:226018
Molecular Function	GO:0005515	protein binding	IPI	J:215888
Molecular Function	GO:0005515	protein binding	IPI	J:173383
Molecular Function	GO:0005515	protein binding	IPI	J:230557
Molecular Function	GO:0005515	protein binding	IPI	J:165478
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Molecular Function	GO:1905030	voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	ISO	J:155856
Molecular Function	GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	ISO	J:155856
Molecular Function	GO:0005249	voltage-gated potassium channel activity	IDA	J:170639
Molecular Function	GO:0005249	voltage-gated potassium channel activity	ISO	J:164563
Molecular Function	GO:0005249	voltage-gated potassium channel activity	ISO	J:155856
Cellular Component	GO:0030424	axon	IDA	J:170639
Cellular Component	GO:0043194	axon initial segment	IDA	J:149503
Cellular Component	GO:0043679	axon terminus	IDA	J:170639
Cellular Component	GO:0043679	axon terminus	IBA	J:265628
Cellular Component	GO:0044305	calyx of Held	ISO	J:155856
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0030425	dendrite	IDA	J:19538
Cellular Component	GO:0030425	dendrite	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:85502
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:106271
Cellular Component	GO:0044224	juxtaparanode region of axon	ISO	J:155856
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:217416
Cellular Component	GO:0044224	juxtaparanode region of axon	IBA	J:265628
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:90136
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:142445
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:142445
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:142445
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:142445
Cellular Component	GO:0030027	lamellipodium	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	IEA	J:60000
Cellular Component	GO:0032809	neuronal cell body membrane	IDA	J:19538
Cellular Component	GO:0043204	perikaryon	IDA	J:19538
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IMP	J:170639
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0034705	potassium channel complex	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0045202	synapse	IEA	J:60000
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IDA	J:85500
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:155856
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:164563
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IBA	J:265628
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0019228	neuronal action potential	ISO	J:155856
Biological Process	GO:0021633	optic nerve structural organization	IMP	J:90136
Biological Process	GO:0097623	potassium ion export across plasma membrane	ISO	J:155856
Biological Process	GO:0071805	potassium ion transmembrane transport	IDA	J:170639
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:155856
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0071805	potassium ion transmembrane transport	IBA	J:265628
Biological Process	GO:0006813	potassium ion transport	IEA	J:72247
Biological Process	GO:0006813	potassium ion transport	IEA	J:60000
Biological Process	GO:0051260	protein homooligomerization	IEA	J:72247
Biological Process	GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	IMP	J:130097
Biological Process	GO:0014059	regulation of dopamine secretion	IMP	J:170639
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:0019233	sensory perception of pain	ISO	J:155856
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247