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GO Annotations Graph
Symbol
Name
ID
Itgal
integrin alpha L
MGI:96606

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0050839cell adhesion molecule bindingISOJ:164563
Molecular FunctionGO:0030369ICAM-3 receptor activityISOJ:164563
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0032403protein complex bindingISOJ:155856
Molecular FunctionGO:0046982protein heterodimerization activityISOJ:155856
Cellular ComponentGO:0009986cell surfaceISOJ:164563
Cellular ComponentGO:0009986cell surfaceISOJ:155856
Cellular ComponentGO:0005911cell-cell junctionIDAJ:205441
Cellular ComponentGO:0009897external side of plasma membraneIDAJ:125138
Cellular ComponentGO:0009897external side of plasma membraneIDAJ:19636
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0001772immunological synapseIDAJ:89810
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0034687integrin alphaL-beta2 complexISOJ:164563
Cellular ComponentGO:0008305integrin complexIEAJ:72247
Cellular ComponentGO:0016020membraneISOJ:164563
Biological ProcessGO:0050798activated T cell proliferationIMPJ:90954
Biological ProcessGO:0007155cell adhesionIEAJ:72247
Biological ProcessGO:0007155cell adhesionIEAJ:60000
Biological ProcessGO:0007166cell surface receptor signaling pathwayIDAJ:125144
Biological ProcessGO:0007160cell-matrix adhesionISOJ:164563
Biological ProcessGO:0007157heterophilic cell-cell adhesion via plasma membrane cell adhesion moleculesISOJ:164563
Biological ProcessGO:0007229integrin-mediated signaling pathwayIEAJ:60000
Biological ProcessGO:0007159leukocyte cell-cell adhesionISOJ:164563
Biological ProcessGO:0007159leukocyte cell-cell adhesionIDAJ:89810
Biological ProcessGO:0007159leukocyte cell-cell adhesionIDAJ:125144
Biological ProcessGO:0007159leukocyte cell-cell adhesionIMPJ:125139
Biological ProcessGO:0050850positive regulation of calcium-mediated signalingIDAJ:125144
Biological ProcessGO:0022409positive regulation of cell-cell adhesionIMPJ:125147
Biological ProcessGO:0042102positive regulation of T cell proliferationIMPJ:125147
Biological ProcessGO:0043113receptor clusteringISOJ:164563
Biological ProcessGO:0022407regulation of cell-cell adhesionIDAJ:125144
Biological ProcessGO:0016337single organismal cell-cell adhesionISOJ:155856
Biological ProcessGO:0002291T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cellISOJ:164563


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/13/2022
MGI 6.21
The Jackson Laboratory