GO Annotations Graph

• Symbol: Gad1
• Name: glutamate decarboxylase 1
• ID: MGI:95632

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016830	carbon-carbon lyase activity	IEA	J:72247
Molecular Function	GO:0016831	carboxy-lyase activity	IEA	J:72247
Molecular Function	GO:0016831	carboxy-lyase activity	IEA	J:60000
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0016595	glutamate binding	ISO	J:155856
Molecular Function	GO:0004351	glutamate decarboxylase activity	ISO	J:164563
Molecular Function	GO:0004351	glutamate decarboxylase activity	ISO	J:155856
Molecular Function	GO:0004351	glutamate decarboxylase activity	IMP	J:40978
Molecular Function	GO:0004351	glutamate decarboxylase activity	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016829	lyase activity	IEA	J:60000
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0030170	pyridoxal phosphate binding	ISO	J:155856
Cellular Component	GO:0030424	axon	IDA	J:101575
Cellular Component	GO:0030424	axon	IDA	J:93895
Cellular Component	GO:0043679	axon terminus	IDA	J:65529
Cellular Component	GO:0043679	axon terminus	IDA	J:65529
Cellular Component	GO:0005938	cell cortex	IDA	J:65529
Cellular Component	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane	TAS	Reactome:R-MMU-9022943
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:92610
Cellular Component	GO:0005737	cytoplasm	IDA	J:158418
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:326687
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:326687
Cellular Component	GO:0060077	inhibitory synapse	IDA	J:211830
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0044306	neuron projection terminus	IDA	J:101575
Cellular Component	GO:0098793	presynapse	IMP	J:326687
Cellular Component	GO:0098793	presynapse	IDA	J:326687
Cellular Component	GO:0048786	presynaptic active zone	IBA	J:265628
Cellular Component	GO:0048786	presynaptic active zone	IDA	J:210135
Cellular Component	GO:0048786	presynaptic active zone	IDA	J:101575
Cellular Component	GO:0048786	presynaptic active zone	ISO	J:211830
Cellular Component	GO:0048786	presynaptic active zone	IDA	J:131058
Cellular Component	GO:0045202	synapse	IDA	J:93895
Biological Process	GO:0019752	carboxylic acid metabolic process	IEA	J:72247
Biological Process	GO:0009449	gamma-aminobutyric acid biosynthetic process	IMP	J:40978
Biological Process	GO:0009449	gamma-aminobutyric acid biosynthetic process	ISO	J:155856
Biological Process	GO:0009449	gamma-aminobutyric acid biosynthetic process	IBA	J:265628
Biological Process	GO:0006538	glutamate catabolic process	ISO	J:164563
Biological Process	GO:0035641	locomotory exploration behavior	IMP	J:215394
Biological Process	GO:0042136	neurotransmitter biosynthetic process	ISO	J:155856
Biological Process	GO:0042136	neurotransmitter biosynthetic process	ISO	J:164563
Biological Process	GO:0042136	neurotransmitter biosynthetic process	IMP	J:40978
Biological Process	GO:0018352	protein-pyridoxal-5-phosphate linkage	ISO	J:164563
Biological Process	GO:0035176	social behavior	IMP	J:215394