GO Annotations Graph

• Symbol: Slc6a1
• Name: solute carrier family 6 (neurotransmitter transporter, GABA), member 1
• ID: MGI:95627

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005283	amino acid:sodium symporter activity	IDA	J:324192
Molecular Function	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity	IMP	J:287185
Molecular Function	GO:0005332	gamma-aminobutyric acid:sodium:chloride symporter activity	IDA	J:324192
Molecular Function	GO:0005332	gamma-aminobutyric acid:sodium:chloride symporter activity	ISO	J:164563
Molecular Function	GO:0005332	gamma-aminobutyric acid:sodium:chloride symporter activity	IDA	J:324197
Molecular Function	GO:0005332	gamma-aminobutyric acid:sodium:chloride symporter activity	IDA	J:3704
Molecular Function	GO:0005332	gamma-aminobutyric acid:sodium:chloride symporter activity	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0015378	sodium:chloride symporter activity	ISO	J:164563
Molecular Function	GO:0015293	symporter activity	IEA	J:60000
Cellular Component	GO:0030424	axon	IDA	J:287185
Cellular Component	GO:0030424	axon	IDA	J:134134
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0030424	axon	IDA	J:93895
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0098982	GABA-ergic synapse	ISO	J:155856
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:95639
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:95639
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	IDA	J:134134
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:129080
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0008306	associative learning	IMP	J:287185
Biological Process	GO:0008306	associative learning	IMP	J:134134
Biological Process	GO:1902476	chloride transmembrane transport	ISO	J:164563
Biological Process	GO:0051939	gamma-aminobutyric acid import	ISO	J:164563
Biological Process	GO:0051939	gamma-aminobutyric acid import	IMP	J:287185
Biological Process	GO:0051939	gamma-aminobutyric acid import	ISO	J:155856
Biological Process	GO:0098658	inorganic anion import across plasma membrane	ISO	J:164563
Biological Process	GO:0007612	learning	ISO	J:155856
Biological Process	GO:0007613	memory	IMP	J:287185
Biological Process	GO:0007613	memory	IMP	J:134134
Biological Process	GO:0032229	negative regulation of synaptic transmission, GABAergic	ISO	J:155856
Biological Process	GO:0098810	neurotransmitter reuptake	ISO	J:155856
Biological Process	GO:0098810	neurotransmitter reuptake	IDA	J:95639
Biological Process	GO:0098810	neurotransmitter reuptake	IMP	J:95639
Biological Process	GO:0006836	neurotransmitter transport	IEA	J:60000
Biological Process	GO:0006836	neurotransmitter transport	IEA	J:72247
Biological Process	GO:0014054	positive regulation of gamma-aminobutyric acid secretion	ISO	J:155856
Biological Process	GO:0010035	response to inorganic substance	ISO	J:164563
Biological Process	GO:0010033	response to organic substance	ISO	J:155856
Biological Process	GO:0014074	response to purine-containing compound	ISO	J:155856
Biological Process	GO:0009636	response to toxic substance	ISO	J:155856
Biological Process	GO:0098719	sodium ion import across plasma membrane	ISO	J:164563
Biological Process	GO:0035725	sodium ion transmembrane transport	IBA	J:265628
Biological Process	GO:0050808	synapse organization	IMP	J:134134