GO Annotations Graph

• Symbol: Gabra6
• Name: gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6
• ID: MGI:95618

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Wed Mar 2 12:11:24 2016.

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008503	contributes_to benzodiazepine receptor activity	ISO	J:155856
Molecular Function	GO:0005254	chloride channel activity	IEA	J:60000
Molecular Function	GO:0008144	drug binding	ISO	J:155856
Molecular Function	GO:0005230	extracellular ligand-gated ion channel activity	IEA	J:72247
Molecular Function	GO:0004890	contributes_to GABA-A receptor activity	ISO	J:155856
Molecular Function	GO:0004890	contributes_to GABA-A receptor activity	IBA	J:161428
Molecular Function	GO:0022851	contributes_to GABA-gated chloride ion channel activity	ISO	J:155856
Molecular Function	GO:0005237	inhibitory extracellular ligand-gated ion channel activity	ISO	J:155856
Molecular Function	GO:0005216	ion channel activity	IEA	J:72247
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0034707	chloride channel complex	IEA	J:60000
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:1902711	GABA-A receptor complex	IBA	J:161428
Cellular Component	GO:0016021	integral component of membrane	IEA	J:72247
Cellular Component	GO:0016021	integral component of membrane	IEA	J:60000
Cellular Component	GO:0005887	integral component of plasma membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0032809	neuronal cell body membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0043235	receptor complex	ISO	J:155856
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0099565	chemical synaptic transmission, postsynaptic	ISO	J:155856
Biological Process	GO:1902476	chloride transmembrane transport	ISO	J:155856
Biological Process	GO:0006821	chloride transport	IEA	J:60000
Biological Process	GO:0006821	chloride transport	IEA	J:72247
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	IEA	J:72247
Biological Process	GO:0034220	ion transmembrane transport	ISO	J:155856
Biological Process	GO:0006811	ion transport	IEA	J:60000
Biological Process	GO:0006811	ion transport	IEA	J:72247
Biological Process	GO:0051291	protein heterooligomerization	ISO	J:155856
Biological Process	GO:0051932	synaptic transmission, GABAergic	ISO	J:155856
Biological Process	GO:0006810	transport	IEA	J:72247
Biological Process	GO:0006810	transport	IEA	J:60000

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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