GO Annotations Graph

• Symbol: Fshr
• Name: follicle stimulating hormone receptor
• ID: MGI:95583

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004963	follicle-stimulating hormone receptor activity	ISO	J:155856
Molecular Function	GO:0004963	follicle-stimulating hormone receptor activity	ISO	J:164563
Molecular Function	GO:0004963	follicle-stimulating hormone receptor activity	IBA	J:265628
Molecular Function	GO:0004963	follicle-stimulating hormone receptor activity	IDA	J:41354
Molecular Function	GO:0004963	follicle-stimulating hormone receptor activity	IDA	J:115870
Molecular Function	GO:0004963	follicle-stimulating hormone receptor activity	IDA	J:55123
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0017046	peptide hormone binding	ISO	J:155856
Molecular Function	GO:0016500	protein-hormone receptor activity	IEA	J:72247
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IDA	J:115870
Cellular Component	GO:0005768	endosome	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0043235	receptor complex	ISO	J:164563
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	IDA	J:115870
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IDA	J:55123
Biological Process	GO:0071711	basement membrane organization	IMP	J:50933
Biological Process	GO:0071372	cellular response to follicle-stimulating hormone stimulus	ISO	J:164563
Biological Process	GO:0042699	follicle-stimulating hormone signaling pathway	ISO	J:164563
Biological Process	GO:0042699	follicle-stimulating hormone signaling pathway	ISO	J:155856
Biological Process	GO:0042699	follicle-stimulating hormone signaling pathway	IBA	J:265628
Biological Process	GO:0042699	follicle-stimulating hormone signaling pathway	IDA	J:55123
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0009755	hormone-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0009992	intracellular water homeostasis	IMP	J:96730
Biological Process	GO:0007626	locomotory behavior	IMP	J:89713
Biological Process	GO:0008584	male gonad development	IBA	J:265628
Biological Process	GO:0045779	negative regulation of bone resorption	IMP	J:129623
Biological Process	GO:0045779	negative regulation of bone resorption	IMP	J:65577
Biological Process	GO:0031175	neuron projection development	IMP	J:109411
Biological Process	GO:0001541	ovarian follicle development	IMP	J:140008
Biological Process	GO:0001541	ovarian follicle development	IMP	J:85611
Biological Process	GO:0001541	ovarian follicle development	IMP	J:50933
Biological Process	GO:0001541	ovarian follicle development	IMP	J:65577
Biological Process	GO:0001541	ovarian follicle development	IMP	J:61909
Biological Process	GO:0001541	ovarian follicle development	IMP	J:70933
Biological Process	GO:0022602	ovulation cycle process	IMP	J:65577
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	IDA	J:55123
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	IMP	J:65577
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	ISO	J:164563
Biological Process	GO:0001545	primary ovarian follicle growth	IMP	J:85611
Biological Process	GO:0060408	regulation of acetylcholine metabolic process	IGI	J:109411
Biological Process	GO:0033044	regulation of chromosome organization	IMP	J:86940
Biological Process	GO:0032350	regulation of hormone metabolic process	IMP	J:109411
Biological Process	GO:0032350	regulation of hormone metabolic process	IMP	J:85611
Biological Process	GO:0032350	regulation of hormone metabolic process	IMP	J:89713
Biological Process	GO:0032350	regulation of hormone metabolic process	IMP	J:85930
Biological Process	GO:0033146	regulation of intracellular estrogen receptor signaling pathway	IMP	J:141278
Biological Process	GO:0033146	regulation of intracellular estrogen receptor signaling pathway	IMP	J:145390
Biological Process	GO:0043408	regulation of MAPK cascade	IMP	J:109411
Biological Process	GO:0045670	regulation of osteoclast differentiation	IMP	J:115870
Biological Process	GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	IMP	J:129217
Biological Process	GO:0010738	regulation of protein kinase A signaling	ISO	J:164563
Biological Process	GO:0001932	regulation of protein phosphorylation	IMP	J:109411
Biological Process	GO:0001932	regulation of protein phosphorylation	IMP	J:109411
Biological Process	GO:0003073	regulation of systemic arterial blood pressure	IMP	J:141287
Biological Process	GO:0060009	Sertoli cell development	IMP	J:96730
Biological Process	GO:0060011	Sertoli cell proliferation	IMP	J:70680
Biological Process	GO:0060011	Sertoli cell proliferation	IMP	J:137427
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0035092	sperm DNA condensation	IMP	J:61957
Biological Process	GO:0035092	sperm DNA condensation	IMP	J:86940
Biological Process	GO:0007286	spermatid development	IMP	J:137005
Biological Process	GO:0007286	spermatid development	IMP	J:70680
Biological Process	GO:0007283	spermatogenesis	IMP	J:50933
Biological Process	GO:0007283	spermatogenesis	IMP	J:137427
Biological Process	GO:0007283	spermatogenesis	IMP	J:86940
Biological Process	GO:0045056	transcytosis	ISO	J:155856
Biological Process	GO:0060065	uterus development	IMP	J:61909