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GO Annotations Graph
Symbol
Name
ID
Flt3
FMS-like tyrosine kinase 3
MGI:95559

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0004896cytokine receptor activityISOJ:155856
Molecular FunctionGO:0004896cytokine receptor activityIMPJ:136209
Molecular FunctionGO:0035259glucocorticoid receptor bindingISOJ:155856
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0043548phosphatidylinositol 3-kinase bindingIDAJ:18780
Molecular FunctionGO:0005515protein bindingIPIJ:23709
Molecular FunctionGO:0005515protein bindingIPIJ:16458
Molecular FunctionGO:0005515protein bindingIPIJ:18780
Molecular FunctionGO:0005515protein bindingIPIJ:56367
Molecular FunctionGO:0005515protein bindingIPIJ:36245
Molecular FunctionGO:0005515protein bindingIPIJ:162445
Molecular FunctionGO:0032403protein complex bindingISOJ:155856
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0004713protein tyrosine kinase activityIDAJ:140548
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Molecular FunctionGO:0004714transmembrane receptor protein tyrosine kinase activityIEAJ:72245
Molecular FunctionGO:0004714transmembrane receptor protein tyrosine kinase activityIEAJ:72247
Molecular FunctionGO:0031625ubiquitin protein ligase bindingIPIJ:213100
Molecular FunctionGO:0031625ubiquitin protein ligase bindingISOJ:155856
Cellular ComponentGO:0009986cell surfaceIDAJ:27743
Cellular ComponentGO:0009986cell surfaceIDAJ:47896
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005829cytosolISOJ:155856
Cellular ComponentGO:0005783endoplasmic reticulumIEAJ:60000
Cellular ComponentGO:0009897external side of plasma membraneIDAJ:203580
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016020membraneIEAJ:72247
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005634nucleusISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:155856
Cellular ComponentGO:0043234protein complexISOJ:155856
Biological ProcessGO:0019882antigen processing and presentationIMPJ:159599
Biological ProcessGO:0030183B cell differentiationIMPJ:170520
Biological ProcessGO:0030183B cell differentiationISOJ:155856
Biological ProcessGO:0030154cell differentiationIEAJ:72247
Biological ProcessGO:0071345cellular response to cytokine stimulusIMPJ:136209
Biological ProcessGO:0071345cellular response to cytokine stimulusISOJ:155856
Biological ProcessGO:0098586cellular response to virusIMPJ:159599
Biological ProcessGO:0035726common myeloid progenitor cell proliferationIMPJ:177063
Biological ProcessGO:0035726common myeloid progenitor cell proliferationISOJ:155856
Biological ProcessGO:0019221cytokine-mediated signaling pathwayIMPJ:136209
Biological ProcessGO:0019221cytokine-mediated signaling pathwayISOJ:155856
Biological ProcessGO:0097028dendritic cell differentiationISOJ:155856
Biological ProcessGO:0097028dendritic cell differentiationIMPJ:136209
Biological ProcessGO:0036145dendritic cell homeostasisIMPJ:159599
Biological ProcessGO:0030097hemopoiesisISOJ:16485
Biological ProcessGO:0048873homeostasis of number of cells within a tissueIGIJ:189096
Biological ProcessGO:0048873homeostasis of number of cells within a tissueIMPJ:159599
Biological ProcessGO:0001776leukocyte homeostasisISOJ:155856
Biological ProcessGO:0001776leukocyte homeostasisIMPJ:136209
Biological ProcessGO:0048535lymph node developmentIMPJ:159599
Biological ProcessGO:0030098lymphocyte differentiationIDAJ:79569
Biological ProcessGO:0046651lymphocyte proliferationIMPJ:136209
Biological ProcessGO:0046651lymphocyte proliferationISOJ:155856
Biological ProcessGO:0002320lymphoid progenitor cell differentiationIGIJ:27238
Biological ProcessGO:0002318myeloid progenitor cell differentiationIGIJ:27238
Biological ProcessGO:0002318myeloid progenitor cell differentiationIMPJ:136209
Biological ProcessGO:0002318myeloid progenitor cell differentiationISOJ:155856
Biological ProcessGO:0002318myeloid progenitor cell differentiationIMPJ:133528
Biological ProcessGO:0045578negative regulation of B cell differentiationIDAJ:108330
Biological ProcessGO:0008285negative regulation of cell proliferationIMPJ:21273
Biological ProcessGO:0032715negative regulation of interleukin-6 productionIMPJ:159599
Biological ProcessGO:0032720negative regulation of tumor necrosis factor productionIMPJ:159599
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0032727positive regulation of interferon-alpha productionIMPJ:159599
Biological ProcessGO:1902741positive regulation of interferon-alpha secretionIMPJ:159599
Biological ProcessGO:0032729positive regulation of interferon-gamma productionIMPJ:159599
Biological ProcessGO:1902715positive regulation of interferon-gamma secretionIMPJ:159599
Biological ProcessGO:0032735positive regulation of interleukin-12 productionIMPJ:159599
Biological ProcessGO:2001184positive regulation of interleukin-12 secretionIMPJ:159599
Biological ProcessGO:0040018positive regulation of multicellular organism growthIMPJ:159599
Biological ProcessGO:0001934positive regulation of protein phosphorylationIGIJ:162445
Biological ProcessGO:0009791post-embryonic developmentIGIJ:189096
Biological ProcessGO:0002328pro-B cell differentiationIMPJ:27238
Biological ProcessGO:0002328pro-B cell differentiationISOJ:155856
Biological ProcessGO:0002328pro-B cell differentiationIMPJ:170520
Biological ProcessGO:0002572pro-T cell differentiationIMPJ:27238
Biological ProcessGO:0046777protein autophosphorylationIDAJ:140548
Biological ProcessGO:0046777protein autophosphorylationIDAJ:18780
Biological ProcessGO:0006468protein phosphorylationIEAJ:72247
Biological ProcessGO:0048536spleen developmentIGIJ:189096
Biological ProcessGO:0007169transmembrane receptor protein tyrosine kinase signaling pathwayIEAJ:72247


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/12/2021
MGI 6.17
The Jackson Laboratory