About   Help   FAQ
GO Annotations Graph
Symbol
Name
ID
Eng
endoglin
MGI:95392

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0036122contributes_to
BMP binding
ISOJ:164563
Molecular FunctionGO:0005534galactose bindingISOJ:164563
Molecular FunctionGO:0005539glycosaminoglycan bindingISOJ:164563
Molecular FunctionGO:0005515protein bindingIPIJ:204744
Molecular FunctionGO:0042803protein homodimerization activityISOJ:164563
Molecular FunctionGO:0042803protein homodimerization activityIPIJ:18318
Molecular FunctionGO:0050431transforming growth factor beta bindingIDAJ:18318
Molecular FunctionGO:0050431contributes_to
transforming growth factor beta binding
ISOJ:164563
Molecular FunctionGO:0050431transforming growth factor beta bindingISOJ:164563
Molecular FunctionGO:0005072transforming growth factor beta receptor, cytoplasmic mediator activityISOJ:164563
Molecular FunctionGO:0005024transforming growth factor beta-activated receptor activityISOJ:164563
Molecular FunctionGO:0034713type I transforming growth factor beta receptor bindingISOJ:164563
Molecular FunctionGO:0005114type II transforming growth factor beta receptor bindingISOJ:164563
Molecular FunctionGO:0005114type II transforming growth factor beta receptor bindingISOJ:155856
Cellular ComponentGO:0009986cell surfaceISOJ:155856
Cellular ComponentGO:0009986cell surfaceISOJ:164563
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0072563endothelial microparticleIDAJ:166919
Cellular ComponentGO:0009897external side of plasma membraneISOJ:164563
Cellular ComponentGO:0005615extracellular spaceISOJ:155856
Cellular ComponentGO:0005615extracellular spaceISOJ:164563
Cellular ComponentGO:0005925focal adhesionISOJ:164563
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005654nucleoplasmISOJ:164563
Cellular ComponentGO:0043235receptor complexISOJ:164563
Biological ProcessGO:0001525angiogenesisIMPJ:73415
Biological ProcessGO:0001525angiogenesisIMPJ:85366
Biological ProcessGO:0048844artery morphogenesisIMPJ:55403
Biological ProcessGO:0007155cell adhesionIEAJ:60000
Biological ProcessGO:0060326cell chemotaxisISOJ:164563
Biological ProcessGO:0016477cell migrationISOJ:164563
Biological ProcessGO:0003273cell migration involved in endocardial cushion formationIMPJ:154475
Biological ProcessGO:0048870cell motilityISOJ:164563
Biological ProcessGO:0022009central nervous system vasculogenesisISOJ:164563
Biological ProcessGO:0070483detection of hypoxiaISOJ:164563
Biological ProcessGO:0070278extracellular matrix constituent secretionISOJ:155856
Biological ProcessGO:0022617extracellular matrix disassemblyISOJ:164563
Biological ProcessGO:0007507heart developmentIMPJ:58502
Biological ProcessGO:0007507heart developmentIMPJ:73415
Biological ProcessGO:0001947heart loopingIMPJ:55403
Biological ProcessGO:0035556intracellular signal transductionISOJ:164563
Biological ProcessGO:0030336negative regulation of cell migrationISOJ:164563
Biological ProcessGO:0001937negative regulation of endothelial cell proliferationISOJ:164563
Biological ProcessGO:0051001negative regulation of nitric-oxide synthase activityISOJ:164563
Biological ProcessGO:0060394negative regulation of pathway-restricted SMAD protein phosphorylationISOJ:164563
Biological ProcessGO:0031953negative regulation of protein autophosphorylationISOJ:164563
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:0001569patterning of blood vesselsIMPJ:55403
Biological ProcessGO:0045766positive regulation of angiogenesisIGIJ:204744
Biological ProcessGO:0045766positive regulation of angiogenesisTASJ:164086
Biological ProcessGO:0030513positive regulation of BMP signaling pathwayISOJ:164563
Biological ProcessGO:0032967positive regulation of collagen biosynthetic processISOJ:155856
Biological ProcessGO:0010628positive regulation of gene expressionISOJ:155856
Biological ProcessGO:0010862positive regulation of pathway-restricted SMAD protein phosphorylationISOJ:164563
Biological ProcessGO:0001934positive regulation of protein phosphorylationISOJ:164563
Biological ProcessGO:0001934positive regulation of protein phosphorylationISOJ:155856
Biological ProcessGO:0003084positive regulation of systemic arterial blood pressureISOJ:164563
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:0006355regulation of transcription, DNA-templatedISOJ:164563
Biological ProcessGO:0017015regulation of transforming growth factor beta receptor signaling pathwayISOJ:155856
Biological ProcessGO:0017015regulation of transforming growth factor beta receptor signaling pathwayTASJ:73415
Biological ProcessGO:0017015regulation of transforming growth factor beta receptor signaling pathwayISOJ:164563
Biological ProcessGO:0001666response to hypoxiaISOJ:164563
Biological ProcessGO:0048745smooth muscle tissue developmentIMPJ:55403
Biological ProcessGO:0007179transforming growth factor beta receptor signaling pathwayICJ:18318
Biological ProcessGO:0001570vasculogenesisIMPJ:58502
Biological ProcessGO:0001570vasculogenesisISOJ:164563
Biological ProcessGO:0001570vasculogenesisIMPJ:55403
Biological ProcessGO:0048845venous blood vessel morphogenesisIMPJ:55403
Biological ProcessGO:0042060wound healingISOJ:164563


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/23/2021
MGI 6.17
The Jackson Laboratory