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GO Annotations Graph
Symbol
Name
ID
Epha2
Eph receptor A2
MGI:95278

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0005003ephrin receptor activityIEAJ:72247
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:200429
Molecular FunctionGO:0005515protein bindingIPIJ:110334
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0004713protein tyrosine kinase activityIEAJ:72247
Molecular FunctionGO:0004713protein tyrosine kinase activityIEAJ:60000
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Molecular FunctionGO:0004714transmembrane receptor protein tyrosine kinase activityISOJ:164563
Cellular ComponentGO:0030054cell junctionIEAJ:60000
Cellular ComponentGO:0042995cell projectionIEAJ:60000
Cellular ComponentGO:0009986cell surfaceISOJ:164563
Cellular ComponentGO:0005925focal adhesionISOJ:164563
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneIEAJ:72247
Cellular ComponentGO:0005887integral component of plasma membraneISOJ:164563
Cellular ComponentGO:0005622intracellularISOJ:164563
Cellular ComponentGO:0031256leading edge membraneISOJ:164563
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Biological ProcessGO:0090630activation of GTPase activityISOJ:164563
Biological ProcessGO:0001525angiogenesisIEAJ:60000
Biological ProcessGO:0006915apoptotic processIEAJ:60000
Biological ProcessGO:0048320axial mesoderm formationIMPJ:69393
Biological ProcessGO:0001568blood vessel developmentIMPJ:69393
Biological ProcessGO:0002043blood vessel endothelial cell proliferation involved in sprouting angiogenesisIMPJ:148922
Biological ProcessGO:0048514blood vessel morphogenesisIMPJ:148922
Biological ProcessGO:0046849bone remodelingIMPJ:175143
Biological ProcessGO:0060444branching involved in mammary gland duct morphogenesisIMPJ:175142
Biological ProcessGO:0007155cell adhesionIEAJ:60000
Biological ProcessGO:0060326cell chemotaxisISOJ:164563
Biological ProcessGO:0030154cell differentiationIEAJ:60000
Biological ProcessGO:0016477cell migrationISOJ:164563
Biological ProcessGO:0050830defense response to Gram-positive bacteriumIMPJ:148922
Biological ProcessGO:0048013ephrin receptor signaling pathwayIDAJ:88877
Biological ProcessGO:0048013ephrin receptor signaling pathwayISOJ:164563
Biological ProcessGO:0048013ephrin receptor signaling pathwayIMPJ:144621
Biological ProcessGO:0006954inflammatory responseIMPJ:148922
Biological ProcessGO:0008630intrinsic apoptotic signaling pathway in response to DNA damageISOJ:164563
Biological ProcessGO:0030216keratinocyte differentiationISOJ:164563
Biological ProcessGO:0070309lens fiber cell morphogenesisIDAJ:144621
Biological ProcessGO:0033598mammary gland epithelial cell proliferationIMPJ:175142
Biological ProcessGO:0016525negative regulation of angiogenesisIMPJ:148922
Biological ProcessGO:0032682negative regulation of chemokine productionIMPJ:148922
Biological ProcessGO:0001818negative regulation of cytokine productionIMPJ:148922
Biological ProcessGO:1901491negative regulation of lymphangiogenesisIMPJ:148922
Biological ProcessGO:0051898negative regulation of protein kinase B signalingISOJ:164563
Biological ProcessGO:0021915neural tube developmentIMPJ:69393
Biological ProcessGO:0030182neuron differentiationIMPJ:91751
Biological ProcessGO:0030182neuron differentiationIDAJ:91751
Biological ProcessGO:0060035notochord cell developmentIMPJ:69393
Biological ProcessGO:0014028notochord formationIMPJ:69393
Biological ProcessGO:0014028notochord formationIGIJ:69393
Biological ProcessGO:0048570notochord morphogenesisIMPJ:69393
Biological ProcessGO:0001649osteoblast differentiationIMPJ:175143
Biological ProcessGO:0030316osteoclast differentiationIDAJ:175143
Biological ProcessGO:0018108peptidyl-tyrosine phosphorylationISOJ:164563
Biological ProcessGO:1904238pericyte cell differentiationIMPJ:148922
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0090004positive regulation of establishment of protein localization to plasma membraneISOJ:164563
Biological ProcessGO:0036342post-anal tail morphogenesisIMPJ:69393
Biological ProcessGO:0043491protein kinase B signalingISOJ:164563
Biological ProcessGO:0006468protein phosphorylationIEAJ:72247
Biological ProcessGO:0045765regulation of angiogenesisIDAJ:110334
Biological ProcessGO:0043535regulation of blood vessel endothelial cell migrationIDAJ:110334
Biological ProcessGO:0033628regulation of cell adhesion mediated by integrinISOJ:164563
Biological ProcessGO:0070372regulation of ERK1 and ERK2 cascadeISOJ:164563
Biological ProcessGO:0010591regulation of lamellipodium assemblyISOJ:164563
Biological ProcessGO:0070848response to growth factorISOJ:164563
Biological ProcessGO:0001501skeletal system developmentIMPJ:69393
Biological ProcessGO:0007169transmembrane receptor protein tyrosine kinase signaling pathwayIEAJ:72247
Biological ProcessGO:0001570vasculogenesisIMPJ:69393


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory