GO Annotations Graph

• Symbol: Dpp4
• Name: dipeptidylpeptidase 4
• ID: MGI:94919

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004177	aminopeptidase activity	IEA	J:60000
Molecular Function	GO:0045499	chemorepellent activity	ISO	J:164563
Molecular Function	GO:0005518	collagen binding	ISO	J:155856
Molecular Function	GO:0008239	dipeptidyl-peptidase activity	ISO	J:155856
Molecular Function	GO:0008239	dipeptidyl-peptidase activity	ISO	J:164563
Molecular Function	GO:0008239	dipeptidyl-peptidase activity	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0042277	peptide binding	ISO	J:155856
Molecular Function	GO:0002020	protease binding	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0004252	serine-type endopeptidase activity	ISO	J:164563
Molecular Function	GO:0008236	serine-type peptidase activity	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0001618	virus receptor activity	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0030139	endocytic vesicle	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0046581	intercellular canaliculus	IDA	J:77485
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0002337	B-1a B cell differentiation	ISO	J:155856
Biological Process	GO:0001662	behavioral fear response	IMP	J:110634
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0043542	endothelial cell migration	ISO	J:164563
Biological Process	GO:0051234	establishment of localization	ISO	J:155856
Biological Process	GO:0035641	locomotory exploration behavior	IMP	J:110634
Biological Process	GO:0010716	negative regulation of extracellular matrix disassembly	ISO	J:164563
Biological Process	GO:0090024	negative regulation of neutrophil chemotaxis	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0002717	positive regulation of natural killer cell mediated immunity	ISO	J:155856
Biological Process	GO:0030163	protein catabolic process	ISO	J:155856
Biological Process	GO:0006508	proteolysis	ISO	J:164563
Biological Process	GO:0006508	proteolysis	IBA	J:265628
Biological Process	GO:0036343	psychomotor behavior	IMP	J:110634
Biological Process	GO:0033632	regulation of cell-cell adhesion mediated by integrin	ISO	J:164563
Biological Process	GO:0002709	regulation of T cell mediated immunity	ISO	J:155856
Biological Process	GO:0001666	response to hypoxia	ISO	J:164563
Biological Process	GO:0042110	T cell activation	ISO	J:164563
Biological Process	GO:0031295	T cell costimulation	ISO	J:164563