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GO Annotations Graph
Symbol
Name
ID
F2
coagulation factor II
MGI:88380

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005509calcium ion bindingIEAJ:72247
Molecular FunctionGO:0016787hydrolase activityIEAJ:60000
Molecular FunctionGO:0008233peptidase activityIMPJ:133917
Molecular FunctionGO:0005515protein bindingIPIJ:26852
Molecular FunctionGO:0005102receptor bindingISOJ:164563
Molecular FunctionGO:0004252serine-type endopeptidase activityISOJ:164563
Molecular FunctionGO:0004252serine-type endopeptidase activityISOJ:155856
Molecular FunctionGO:0004252serine-type endopeptidase activityIDAJ:139818
Molecular FunctionGO:0008236serine-type peptidase activityIEAJ:60000
Molecular FunctionGO:0070053thrombospondin receptor activityISOJ:164563
Cellular ComponentGO:0072562blood microparticleISOJ:164563
Cellular ComponentGO:0005829cytosolISOJ:164563
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0031012extracellular matrixISOJ:155856
Cellular ComponentGO:0005576extracellular regionIEAJ:72247
Cellular ComponentGO:0005615extracellular spaceISOJ:164563
Cellular ComponentGO:0005615extracellular spaceISOJ:155856
Biological ProcessGO:0006953acute-phase responseIEAJ:60000
Biological ProcessGO:0007596blood coagulationISOJ:155856
Biological ProcessGO:0007166cell surface receptor signaling pathwayISOJ:164563
Biological ProcessGO:0042730fibrinolysisISOJ:164563
Biological ProcessGO:0007599hemostasisIEAJ:60000
Biological ProcessGO:0048712negative regulation of astrocyte differentiationISOJ:164563
Biological ProcessGO:0045861negative regulation of proteolysisISOJ:164563
Biological ProcessGO:0030168platelet activationISOJ:164563
Biological ProcessGO:0030168platelet activationIDAJ:121278
Biological ProcessGO:0030194positive regulation of blood coagulationISOJ:155856
Biological ProcessGO:0030194positive regulation of blood coagulationISOJ:164563
Biological ProcessGO:0030307positive regulation of cell growthIGIJ:139818
Biological ProcessGO:0008284positive regulation of cell proliferationIGIJ:139818
Biological ProcessGO:0032967positive regulation of collagen biosynthetic processISOJ:164563
Biological ProcessGO:0014068positive regulation of phosphatidylinositol 3-kinase signalingIGIJ:139818
Biological ProcessGO:1900738positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathwayISOJ:164563
Biological ProcessGO:0001934positive regulation of protein phosphorylationISOJ:164563
Biological ProcessGO:2000379positive regulation of reactive oxygen species metabolic processISOJ:164563
Biological ProcessGO:0051281positive regulation of release of sequestered calcium ion into cytosolISOJ:164563
Biological ProcessGO:0006508proteolysisIEAJ:60000
Biological ProcessGO:0006508proteolysisIEAJ:72247
Biological ProcessGO:0008360regulation of cell shapeIGIJ:139818
Biological ProcessGO:0051480regulation of cytosolic calcium ion concentrationISOJ:164563
Biological ProcessGO:0010468regulation of gene expressionIDAJ:138062
Biological ProcessGO:0009611response to woundingISOJ:164563
Biological ProcessGO:0070493thrombin receptor signaling pathwayISOJ:139818


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/10/2020
MGI 6.16
The Jackson Laboratory