GO Annotations Graph

• Symbol: Cdh2
• Name: cadherin 2
• ID: MGI:88355

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0045294	alpha-catenin binding	ISO	J:164563
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:164563
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:155856
Molecular Function	GO:0045296	cadherin binding	IBA	J:265628
Molecular Function	GO:0005509	calcium ion binding	IDA	J:48283
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0019899	enzyme binding	IPI	J:213556
Molecular Function	GO:0045295	gamma-catenin binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:245287
Molecular Function	GO:0042802	identical protein binding	IPI	J:245281
Molecular Function	GO:0042802	identical protein binding	IPI	J:245244
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0050998	nitric-oxide synthase binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:268027
Molecular Function	GO:0005515	protein binding	IPI	J:123218
Molecular Function	GO:0005515	protein binding	IPI	J:98470
Molecular Function	GO:0005515	protein binding	IPI	J:142596
Molecular Function	GO:0005515	protein binding	IPI	J:93341
Molecular Function	GO:0005515	protein binding	IPI	J:114547
Molecular Function	GO:0005515	protein binding	IPI	J:72775
Molecular Function	GO:0005515	protein binding	IPI	J:158573
Molecular Function	GO:0005515	protein binding	IPI	J:98470
Molecular Function	GO:0005515	protein binding	IPI	J:158573
Molecular Function	GO:0005515	protein binding	IPI	J:98470
Molecular Function	GO:0005515	protein binding	IPI	J:145745
Molecular Function	GO:0005515	protein binding	IPI	J:91529
Molecular Function	GO:0005515	protein binding	IPI	J:145745
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0019901	protein kinase binding	IPI	J:197851
Molecular Function	GO:0019903	protein phosphatase binding	IPI	J:114547
Molecular Function	GO:1990782	protein tyrosine kinase binding	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0003723	RNA binding	IDA	J:241317
Cellular Component	GO:0005912	adherens junction	ISO	J:164563
Cellular Component	GO:0005912	adherens junction	ISO	J:155856
Cellular Component	GO:0005912	adherens junction	IDA	J:93314
Cellular Component	GO:0005912	adherens junction	IBA	J:265628
Cellular Component	GO:0005912	adherens junction	IDA	J:78855
Cellular Component	GO:0005912	adherens junction	IDA	J:253677
Cellular Component	GO:0005912	adherens junction	IDA	J:83082
Cellular Component	GO:0005912	adherens junction	IDA	J:113146
Cellular Component	GO:0005912	adherens junction	IDA	J:83398
Cellular Component	GO:0005912	adherens junction	IDA	J:135108
Cellular Component	GO:0045177	apical part of cell	IBA	J:265628
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:180706
Cellular Component	GO:0016327	apicolateral plasma membrane	IDA	J:253677
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:216935
Cellular Component	GO:0016342	catenin complex	ISO	J:164563
Cellular Component	GO:0016342	catenin complex	IBA	J:265628
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:216499
Cellular Component	GO:0005911	cell-cell junction	IDA	J:265612
Cellular Component	GO:0005911	cell-cell junction	IDA	J:297286
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0005911	cell-cell junction	IDA	J:170926
Cellular Component	GO:0030864	cortical actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0030057	desmosome	IDA	J:93314
Cellular Component	GO:0005916	fascia adherens	ISO	J:155856
Cellular Component	GO:0005916	fascia adherens	IDA	J:73178
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0014704	intercalated disc	IDA	J:197851
Cellular Component	GO:0014704	intercalated disc	ISO	J:155856
Cellular Component	GO:0014704	intercalated disc	IDA	J:227218
Cellular Component	GO:0014704	intercalated disc	IDA	J:127606
Cellular Component	GO:0014704	intercalated disc	IBA	J:265628
Cellular Component	GO:0014704	intercalated disc	IDA	J:239053
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0030027	lamellipodium	IBA	J:265628
Cellular Component	GO:0030027	lamellipodium	IDA	J:87902
Cellular Component	GO:0016020	membrane	ISO	J:156343
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:227218
Cellular Component	GO:0005886	plasma membrane	IDA	J:48283
Cellular Component	GO:0005886	plasma membrane	IDA	J:128085
Cellular Component	GO:0044853	plasma membrane raft	IDA	J:220503
Cellular Component	GO:0014069	postsynaptic density	IDA	J:162856
Cellular Component	GO:0014069	postsynaptic density	IBA	J:265628
Cellular Component	GO:0099634	postsynaptic specialization membrane	ISO	J:155856
Cellular Component	GO:0048787	presynaptic active zone membrane	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0042383	sarcolemma	IDA	J:197851
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IDA	J:86623
Cellular Component	GO:0030315	T-tubule	ISO	J:155856
Biological Process	GO:0034332	adherens junction organization	IBA	J:265628
Biological Process	GO:0048514	blood vessel morphogenesis	IBA	J:265628
Biological Process	GO:0048514	blood vessel morphogenesis	IMP	J:98422
Biological Process	GO:0007420	brain development	IBA	J:265628
Biological Process	GO:0048854	brain morphogenesis	IGI	J:215584
Biological Process	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	ISO	J:155856
Biological Process	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IBA	J:265628
Biological Process	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IDA	J:87101
Biological Process	GO:0007155	cell adhesion	IDA	J:87902
Biological Process	GO:0007155	cell adhesion	IDA	J:84125
Biological Process	GO:0016477	cell migration	IDA	J:87101
Biological Process	GO:0000902	cell morphogenesis	IBA	J:265628
Biological Process	GO:0098609	cell-cell adhesion	ISO	J:155856
Biological Process	GO:0098609	cell-cell adhesion	IDA	J:48283
Biological Process	GO:0098609	cell-cell adhesion	ISO	J:164563
Biological Process	GO:0044331	cell-cell adhesion mediated by cadherin	IDA	J:213556
Biological Process	GO:0044331	cell-cell adhesion mediated by cadherin	IBA	J:265628
Biological Process	GO:0007043	cell-cell junction assembly	IMP	J:297286
Biological Process	GO:0007043	cell-cell junction assembly	IBA	J:265628
Biological Process	GO:0021987	cerebral cortex development	IGI	J:215584
Biological Process	GO:0010001	glial cell differentiation	IDA	J:213556
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IDA	J:14830
Biological Process	GO:0048872	homeostasis of number of cells	IGI	J:215584
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	IBA	J:265628
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	IDA	J:87101
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	IDA	J:14830
Biological Process	GO:0090497	mesenchymal cell migration	IMP	J:128085
Biological Process	GO:0050804	modulation of chemical synaptic transmission	ISO	J:155856
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IGI	J:145745
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IGI	J:145745
Biological Process	GO:0014032	neural crest cell development	IMP	J:297286
Biological Process	GO:0060563	neuroepithelial cell differentiation	IGI	J:215584
Biological Process	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly	IMP	J:161278
Biological Process	GO:0097150	neuronal stem cell population maintenance	IDA	J:213556
Biological Process	GO:0043410	positive regulation of MAPK cascade	IGI	J:158573
Biological Process	GO:0043410	positive regulation of MAPK cascade	IGI	J:158573
Biological Process	GO:0043410	positive regulation of MAPK cascade	IGI	J:158573
Biological Process	GO:2000809	positive regulation of synaptic vesicle clustering	IMP	J:161278
Biological Process	GO:0072659	protein localization to plasma membrane	IDA	J:220503
Biological Process	GO:0060019	radial glial cell differentiation	IGI	J:215584
Biological Process	GO:0050770	regulation of axonogenesis	ISO	J:155856
Biological Process	GO:0050770	regulation of axonogenesis	IBA	J:265628
Biological Process	GO:0031641	regulation of myelination	ISO	J:155856
Biological Process	GO:0070445	regulation of oligodendrocyte progenitor proliferation	IGI	J:215584
Biological Process	GO:1902897	regulation of postsynaptic density protein 95 clustering	IMP	J:161278
Biological Process	GO:0032880	regulation of protein localization	ISO	J:155856
Biological Process	GO:0035023	regulation of Rho protein signal transduction	ISO	J:155856
Biological Process	GO:0009966	regulation of signal transduction	IEA	J:72247
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	ISO	J:155856
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	IBA	J:265628
Biological Process	GO:0051146	striated muscle cell differentiation	IGI	J:158573
Biological Process	GO:0051146	striated muscle cell differentiation	IGI	J:158573
Biological Process	GO:0051146	striated muscle cell differentiation	IGI	J:158573
Biological Process	GO:0051146	striated muscle cell differentiation	IGI	J:158573
Biological Process	GO:0007416	synapse assembly	ISO	J:155856
Biological Process	GO:0007416	synapse assembly	IBA	J:265628
Biological Process	GO:0097091	synaptic vesicle clustering	IMP	J:331911
Biological Process	GO:0021537	telencephalon development	IGI	J:215584
Biological Process	GO:0003323	type B pancreatic cell development	IMP	J:297286